MR医学影像文献Zhuang-2016-Intraoperative Multi-Information-G.pdfVIP

Original Article Intraoperative Multi-Information-Guided Resection of Dominant-Sided Insular Gliomas in a 3-T Intraoperative Magnetic Resonance Imaging Integrated Neurosurgical Suite Dong-Xiao Zhuang, Jin-Song Wu, Cheng-Jun Yao, Tian-Ming Qiu, Jun-Feng Lu, Feng-Ping Zhu, Geng Xu, Wei Zhu, Liang-Fu Zhou - OBJECTIVE: To evaluate the clinical application of 3-T 90% to 93% (P [ 0.008) in all cases, and from 88% to 92% intraoperative magnetic resonance imaging (iMRI), awake (P [ 0.018) in low-grade gliomas. The use of iMRI also craniotomy, multimodal functional mapping, and intra- resulted in an increase in the percentage of gross and near operative neurophysiologic monitoring (IONM) for resec- total resection from 53% to 77% (P [ 0.016). The rates of tion of dominant-sided insular gliomas. permanent language and motor deficits resulting from tumor removal were 11% and 7.1%, respectively. - METHODS: From March 2011 to June 2013, 30 gliomas involving the dominant insular lobe were resected in the - CONCLUSIONS: The combination of iMRI, awake IMRIS 3.0-T iMRI integrated neurosurgical suite. For 20 craniotomy, multimodal brain mapping, and IONM tailored patients, awake craniotomy with cortical electrical stim- for each patient permits the maximal safe resection of ulation mapping was performed to locate the language dominant-sided insular glioma. areas. For 10 patients who were not suitable for awake surgery, general anesth