原发性脑淋巴瘤的mri影像表现与诊断-海南医学.pdfVIP

海南医学2013年12月第24卷第23期 doi:10.3969/j.issn.1003-6350.2013.23.1450 ·论 著· 原发性脑淋巴瘤的MRI影像表现与诊断 解 磊，杜尚云 (宿州市第一人民医院CT MRI 室，安徽 宿州 234000) 【摘要】 目的 探讨原发性脑淋巴瘤(PLB)的MRI 影像表现，以提高对该病的诊断率。方法 回顾分析经 手术病理及临床治疗证实的12例PLB 患者(观察组)的临床资料，另外选择在我院就诊的20 例颅内转移瘤患者作 为对照组。结果 12例PLB 患者中单发病灶者8 例，多发病灶者4 例，共计18个病灶，其中位于基底节区5 个、 大脑半球10个和小脑3 个。观察组肿瘤病灶累及深部脑组织患者8 例，明显高于对照组的2 例(P0.05) ；观察组 多发病灶呈区域性分布的比例明显高于对照组(P0.05) ；观察组在低信号、等或稍高信号、高信号方面与对照 组差异有统计学意义(P0.05) ；观察组患者中具有明显囊变、坏死特征性改变1 例，明显低于对照组的14 例 (P0.05) ；观察组患者有9 例肿瘤组织在MRI 增强扫描中有局部刺状突起，明显高于对照组的1 例(P0.05) 。 结论 脑原发性淋巴瘤的MRI 表现具有一定的特征性，在与其他颅内肿瘤鉴别中具有一定的诊断价值。 【关键词】 原发性脑淋巴瘤；磁共振成像；影像表现 【中图分类号】R739.44 【文献标识码】A 【文章编号】 1003—6350（2013 ）23—3488—04 MRIappearanceanddiagnosisofprimarylymphomaofthebrain.XIELei, DUShang-yun.CTMRIRoom, the FirstPeoplesHospitalofSuzhouCity,Suzhou234000,Anhui,CHINA 【Abstract】 Objective To investigate the MRI appearance of primary lymphoma of the brain (PLB), in order to improve the diagnosis rate. Methods The clinical data of 12 patients with PLB (the study group) were retrospec- tively analyzed, and 20 patients with brain metastases were selected as the control group. Results Of the 12 cases, 8 were single lesion, 4 were multiple lesions, with a total of 18 lesions, of which 5 were located in basal ganglia, 10 in cerebral hemispheres and 3 in cerebellum. Eight patients in the study group were with tumor lesions involving the deep brain tissue, significantly more than 2 patients in the control group (P0.05). The proportion of multiple lesions showed that the regional distribution in the study group was significantly high