【精选】Synthesis of 8-geranyloxypsoralen analogues and their as inhibitors of CYP3A4evaluation.pdfVIP

Bioorganic Medicinal Chemistry 14 (2006) 3865–3871 Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4 E. C. Row,a, S. A. Brown,b, A. V. Stachulskib, and M. S. Lennarda,* aAcademic Unit of Clinical Pharmacology, The University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK bSAFC Pharma (formerly Ultrafine), Synergy House, Manchester Science Park, Manchester, UK Received 1 December