PCT、CRP对于重症颅脑损伤患者肺部感染早期诊断价值的研究Study on the value of PCT and CRP in early diagnosis of pulmonary infection in patients with severe craniocerebral injury.pdfVIP
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PCT、CRP对于重症颅脑损伤患者肺部感染早期诊断价值的研究Study on the value of PCT and CRP in early diagnosis of pulmonary infection in patients with severe craniocerebral injury
PCI、CRP对于重症颅脑损伤患者肺部感染早期诊断价值的研究
捅要
目的:探讨PCT、CRP等炎性标记物实验室检测对重症颅脑损伤患者肺部感染
早期诊断的价值。
方法:选取外伤后直接收住重症医学科的63例重症颅脑损伤患者,其中男39
留取血标本,然后收集患者每日的临床资料,记录体温峰值(℃)、白细胞计数(wBC)
影像检查结果作为观察指标列表。所有参数设置与实验步骤均严格按其操作规程进
行。根据最终临床特征和实验室检查结果,将患者分为非感染组和感染组。所有数
据以SPSSl3.0统计软件处理,统计学处理正态分布的计量资料用x±S表示,2个
样本均数比较采用两组完全随机化设计资料均数的t检验,检验水准Q=0.05。P
O。05为差异有统计学意义。结合指标列表探讨上述指标对重症颅脑损伤患者肺部感
染早期诊断及治疗的临床意义。
结果:1.感染组血清中PCT检测阳性率为97.3%,CRP检测阳性率为100%,
CRP对重症颅脑损伤患者肺部感染早期诊断灵敏度分别为76%、81%,特异度分别
为69%、15%。3.联合检测灵敏度、特异度分别为81%、77%。
结论:PCT联合CRP检测阳性率及特异性高,故联合监测重症颅脑损伤患者
血清中PCT和CRP含量可作为ICU重症颅脑损伤患者继发肺部感染早期较特异和敏
感指标。
硕士研究生:许涛(急诊医学)
指导教师:孙运波教授
关键词:C一反应蛋白;降钙素原;重症颅脑损伤:肺部感染
valueof for withseverehead
PCT,CRP
Earlydiagnostic patients
injuryinfection
lung
the andother markers
PCT,CRP inflammatory
Objective:Toinvestigate
testvaluesfor infectionin withseveretraumaticbrain
laboratory lung patients
diagnosis.
injuryearly
Methods:AfterdirecttraumatolivecloseCriticalCareMedicine63
selecting
withseveretraumaticbrain 39malesand24
patients injurypatients,including
14to85 fromICU
females,agedyears,meanage(40士4.25)yearsold.Specimens
withinlhafterblood werethencollectedclinical
admission samples daily data,record
the bloodcell
peak(℃),whiteCOunt(WBC)andneutrophilsfNEU),
temperature
acute reactive calcium
p
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