外文翻译-实验室的一个显示器：使用液晶显示器（LCD）的新的微粒操纵平台.docVIP

外文文献 Lab-on-a-display:a new microparticle manipulation platform using a liquid crystal display (LCD) Wonjae Choi·Se-Hwan Kim·Jin Jang Je-Kyun Park Received: 20 June 2006 / Accepted: 8 September 2006 / Published online: 11 October 2006⑥Springer-Verlag 2006 Abstract This paper reports a new portable microfluidic platform, lab-on-a-display, that microparticles are manipulated by optoelectronic tweezers(OET) on a liquid crystal display (LCD). The OET has been constructed by assembling a ground layer, a liquid chamber, and a photoconductive layer. Without lens or optical alignments, the LCD image directly forms virtual electrodes on the photoconductive layer for dielectrophoretic manipulation . The lab-on-a-display was first realized by a conventional monochromatic LCD module and a light source brighter than 5,000 lux.It was successfully applied to the programmable manipulation of 45 μm polystyrene beads; more than 100 particles were transported with an optical image-driven control, following the moving edge of the image at every moment. The effects of bead size and bias voltage on the manipulation speed were also investigated. Due to the portability and compatibility for disposable applications, this new platform has potential for programmable particle manipulation or chip-based bioprocessing including cell separation and bead-based analysis. Keywords Microfluidics, Lab-on-a-display，Liquid crystal display (LCD), Optoelectronic, tweezers, Dielectrophoresis, Particle manipulation 1 Introduction The manipulation of biological cells and microparticles plays an important role in many biological applications (Verpoorte 2003; Dittrich and Manz 2006). Dielectrophoresis (DEP) is a favorable phenomenon for the manipulation of various dielectric particles (Hughes 2002; Krupke et al. 2003; Washizu et al. 1994). Generally, DEP utilizes the interaction force between nonuniform electric field and the induced dipole moment of the particle. Due to its ability to handle cel