移植肾功能延迟恢复的病理变化与中医证型关系-中国中医药信息杂志.pdfVIP

2015 年6月第 22卷第6期 中国中医药信息杂志 ·39· 移植肾功能延迟恢复的病理变化与中医证型关系 聂峰,孙煦勇,胡赟,朱峪英,黄志成,杨建均,吴风富 解放军第 303医院,广州军区器官移植中心,广西移植医学重点实验室,广西 南宁 530021 摘要：目的 探讨移植肾功能延迟恢复 (DGF)的病理诊断与中医辨证之间的联系,为丰富中医辨证模式及其 创新提供依据。方法 对 57 例肾移植术后 DGF 并行移植肾穿刺病理活检的患者进行中医辨证,将所得证型与相 应病理结果进行对照分析。结果 57 例患者辨为脾肾气虚、气滞血瘀、肝肾阴虚、气阴两虚 4 种证型,病理活 检诊断为急性肾小管上皮变性坏死、钙调磷酸酶抑制剂中毒及急性排斥反应,各病理诊断与中医证型间存在数 量上的对应关系。结论 病理诊断与中医证型存在内在联系,可以作为中医辨证的参考依据。 关键词：肾移植；移植肾功能延迟恢复；病理诊断；中医辨证 DOI：10.3969/j.issn.1005-5304.2015.06.012 中图分类号：R277.52 文献标识码：A 文章编号：1005-5304(2015)06-0039-04 Study on Relationship Between Pathological Changes and TCM Syndrome Differentiation of Delayed Graft Function after Renal Transplantation NIE Feng, SUN Xu-yong, HU Yun, ZHU Yu-ying, HUANG Zhi-cheng, YANG Jian-jun, WU Feng-fu (303 Hospital of PLA, Center of Organ Transplantation in Guangzhou Military Region, Guangxi Key Laboratory for Transplantation Medicine, Nanning 530021, China) Abstract ：Objective To provide references for enriching and innovating patterns of TCM syndrome differentiation by exploring the relationship between pathological changes and TCM syndrome differentiation of delayed graft function (DGF) after renal transplantation. Methods Totally 57 patients with DGF after renal transplantation who were diagnosed by pathological biopsy were also diagnosed by TCM doctors to obtain TCM syndromes. And the pathological diagnoses were compared with the distribution of TCM syndromes to discuss the relationship between them. Results All the patients were classified into four TCM syndromes ：spleen-kidney qi deficiency, liver-kidney yin deficiency, qi-stagnation and blood stasis, and deficiency of both qi and yin. The results of pathological biopsy were as follows：acute tubular necrosis, calcineurin inhibitor