脑血栓形成合并阻塞性睡眠呼吸暂停低通气综合征患病率调查及对神经功能障碍的影响.docVIP

脑血栓形成合并阻塞性睡眠呼吸暂停低通气综合征患病率调查及对神经功能障碍的影响 上海市静安区老年医院20004任蕾杜井波 李庆云摘要目的 方法 对例患者。结果 P0.05）。脑血栓形成患者OSAHS的患病率高于对照组(52.2% vs 25.0%,P0.01）。脑血栓形成合并OSAHS的患者MMSE评分较单纯OSAHS患者明显下降（P＜0.01）。脑血栓形成合并OSAHS患者中国神经功能缺损评定量表及欧洲脑卒中量表评分比单纯脑血栓形成者明显下降（P＜0.01）。 结论关键词：neurological and recognition function Lei Ren 1 ，kai Wang2 , Jingbo Du 1， Zhen Li1 ,Qingyun Li 3 1 Department of Respiratory Medicine, Shanghai Jingan Geriatric Hospital, 200042 ,China. 2 Department of Rehabilitation Medicine, Shanghai Jingan Geriatric Hospital, 200042 ,China. 3 Department of Respiratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025 ,China. [Abstract]Objective: To investigate the prevalence of cerebral thrombosis combined with obstructive sleep apnea-hypopnea syndrome, and the influence on recognition and neurological function. Methods: 46 patients with cerebral thrombosis and 32 controls were tested by polysomnography (PSG). MMSE, European stroke scale and Chinese Neurological Impairment Scale were recorded and the influence of OSAHS were analyzed. Results: AHI of patients with cerebral thrombosis are significantly higher than those in control group (52.2% vs 25.0%, P0.05）. The score of MMSE and European Stroke Scale and Chinese Neurological Impairment Scale of patients with cerebral thrombosis combined with OSAHS are significantly lower than those of cerebral thrombosis without OSAHS. Conclusion: Higher prevalence of cerebral thrombosis combined with OSAHS were found in patients. Combining with OSAHS has influence on recognition and neurological function of patients with cerebral thrombosis. [Key words]: cerebral thrombosis; obstructive sleep apnea-hypopnea syndrome (OSAHS); mini-mental state examination ,MMSE ;The European Stroke Scale; The Chinese Neurological Impairment Scale 阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome, OSAHS)表现为睡眠打鼾并伴有呼吸暂停和呼吸表浅，夜间反复发生低氧血症、高碳酸血症和睡眠结构紊乱。已有报道显示OSAHS是脑血栓形成的独立危险因素，但对于脑血栓形成本身是否增加OSAHS发病的研究较少。脑血栓形成患