尘肺病患者医院感染及其危险因素分析.docVIP

尘肺病患者医院感染危险因素分析 周宇燕，高 杰，李智民 （518001 广东 深圳深圳市职业病防治院职业病科 [摘要] 目的　探讨尘肺病住院患者发生医院感染的状况并分析其危险因素。方法　对我院职业病科2006年1月2013年12月确诊为尘肺的138例住院患者病历资料进行回顾性分析。结果　138例尘肺病患者医院感染发生率为28.26%；检出病原菌16株，检出率为37.21%。单因素分析结果显示，尘肺病分期、住院时间、不合理使用广谱抗生素是尘肺病患者发生医院感染的危险因素。多因素分析结果显示，尘肺期、住院时间、不合理使用广谱抗生素是其危险因素。结论　尘肺病住院患者医院感染发生率较高，尘肺病、住院时间、不合理使用广谱抗生素是尘肺病患者发生医院感染的危险因素蛋白。 尘肺；医院感染；危险因素 [文献标志码] A Dangerous factors analysis of pneumoconiosis patients with nosocomial infection Zhou Yuyan，G Jie，L Zhimin（ , Guangdong,China） Abstract] Objective To analyze the nosocomial infection situation of the pneumoconiosis patients and the dangerous factors. Methods Retrospectively analyze the cases of the pneumoconiosis patients from January 2006 to December2013 in our hospital. Results For the pneumoconiosis patients, the rate of nosocomial infection was 28.26%；16 strains of pathogenic bacteria were detected out, the detection rate was 37.21%.Single factor analysis showed：pneumoconiosis staging, hospital stays, unreasonable use of broad-spectrum antibiotics，hypoproteinemia and smoking were the dangerous factors of nosocomial infection of the pneumocomiosis patients. Multiple factors analysis showed：pneumoconiosis staging（OR=0.019,P=0.004, 95% CI:0.001~0.278）, hospital stays（OR=1.085,P=0.001, 95% CI:1.035~1.137）, and unreasonable use of broad-spectrum antibiotics（OR=1.112,P=0.024, 95% CI:1.014~1.22）were the main independent dangerous factors ，but the serum albumin was a protective factor（OR=0.841,P=0.012, 95% CI:0.734~0.963）. Conclusion The rate of nosocomial infection of the pneumoconiosis patients in hospital was higher. Pneumoconiosis staging, hospital stays and unreasonable use of broad-spectrum antibiotics were the main independent dangerous factors, but the serum albumin was a protective factor. [Key words] Pneumoconiosis；Nosocomial infection；Dangerous factorNational key clinical subject construction projects for occupational diseases (WY2011873); Shenzhen major di