三种全身麻醉药物诱导对高龄患者心功能的影响分析.docVIP

精品论文 参考文献 三种全身麻醉药物诱导对高龄患者心功能的影响分析 （陕西省延安市人民医院药剂科 陕西 延安 716000） 【摘 要】目的：探讨高龄患者使用咪达唑仑、丙泊酚和七氟醚三种全身麻醉药物诱导对高龄患者心功能的影响，并为深入的研究提供一定依据。方法：选取我院于2011年1月～2013年1月收治的120例行非心脏手术和全身麻醉药物诱导的患者，随机将其分为A、B、C三组，其中A组使用咪达唑仑；B组使用丙泊酚；C组使用七氟醚，对患者进行全身麻醉诱导；并在T0(麻醉诱导前）、T1（插管后2分钟）、T2（插管后10分钟）3个时间段对患者的各项指标进行监测，分别进行统计分析。结果：通过三种全身麻醉药物诱导，可知A组和C组患者在使用后，各时间段的SVR明显下降，差异显著，有统计学意义（Plt;0.05)，且将A组和C组患者的SVR相对比，C组患者SVR的下降明显高于A组患者，有统计学意义（Plt;0.05)；B组患者在使用后，各时间段的HR、SV、SVR以及ET差异显著，有统计学意义（Plt;0.05)。结论：通过研究发现，咪达唑仑、丙泊酚和七氟醚三种全身麻醉药均会对高龄患者的心功能产生一定影响，其中咪达唑仑的影响最小，丙泊酚对患者的影响最大。 【关键词】咪达唑仑；丙泊酚；七氟醚；高龄患者；心功能 【中图分类号】R614 【文献标识码】A 【文章编号】1004-6194（2015）02-0086-02 Three kinds of general anesthesia drug analysis induced effects on heart function in aged patients Zhang Juan Cheng bai duo Yanan Peoples Hospital of Shaanxi Province Department of pharmacy hundreds FLOWER ZIP Code: 716000 【Abstract】Objective: elderly patients with midazolam, propofol and sevoflurane induced three kinds of systemic effects on heart function in aged patients with drug anesthesia, and to provide references for further study. Methods: selected in our hospital in 2011 January ~ 2013 January admitted 120 cases of non cardiac operation and general anesthesia in patients with drug induced, and randomly divided into A, B, C three groups, the A group used midazolam; group B used propofol; group C of sevoflurane, performed on patients with general anesthesia induction; and in the T0 (before anesthesia (T1), 2 minutes after intubation (T2), 10 min after intubation) 3 time intervals to monitor various indexes were, respectively, statistical analysis. Results: through three general anesthesia induction, we know that A group and C group patients after use, each time SVR decreased significantly, the difference was significant, with statistical significance (Plt;0.05), and the A group and the C group patients with SVR compared to C group, decreased in patients with SVR was significantly higher than that in group A patients, there were sta