厄贝沙坦联合氨氯地平治疗原发性高血压患者的疗效研究.docVIP

精品论文 参考文献 厄贝沙坦联合氨氯地平治疗原发性高血压患者的疗效研究 王小燕 　　（河北省围场满族蒙古族自治县医院药剂科 河北 承德 068450） 　　【摘要】目的：观察厄贝沙坦联合氨氯地平治疗原发性高血压病的临床疗效，评价其临床用药效果及安全性。方法：随机选取2010年1月—2013年12月间我院收治的原发性高血压病患者106例，随机分为对照组51例和观察组55例，其中对照组患者仅给予氨氯地平单纯治疗，而观察组患者给予同对照组治疗的基础上加用厄贝沙坦联合治疗，对两组患者的临床疗效进行对比分析。结果：本研究106例原发性高血压病患者经1个疗程治疗后，对照组患者的总有效率为72.55%，观察组患者的总有效率为96.36%，观察组疗效优于对照组，且差异显著，具有统计学意义（P＜O.O5）；同时，观察组的收缩压、舒张压下降幅度比对照组更明显。结论：应用厄贝沙坦联合氨氯地平治疗原发性高血压病疗效显著，且副作用较少，临床用药安全性高，值得推广应用。 　　【关键词】厄贝沙坦；氨氯地平；原发性高血压；疗效 　　【中图分类号】R453 【文献标识码】A 【文章编号】2095-1752（2015）03-0055-02 　　He sand temple with amlodipine therapy study the curative effect of patients with essential hypertension (eh) Wang Xiaoyan. Weichang County hospitals in Hebei province, Chengde 068450, China 　　【Abstract】Objective Observation he sand temple with amlodipine therapy of primary hypertensions clinical curative effect, evaluation the clinical drug efficacy, and safety. Methods Randomly selected from January 2010 to December 2010 essential hypertension patients of our hospital between 106 cases, 51 cases were randomly divided into control group and observation group 55 cases, among them the control group patients give amlodipine only simple treatment, the observation group of patients with the control group was given on the basis of combined with urban bay sand combination therapy. Results 106 cases of primary hypertension patients after one course of treatment, the control group, the total effective rate was 72.55% in patients with observation group of patients with the total effective rate was 96.36%, curative effect observation group is better than that of control group, and significant difference, statistically significant (P lt; 0.05); At the same time, the systolic pressure, diastolic blood pressure drop in observation group was better than control group obviously. Conclusions Application of er bei sha Tanzania with amlodipine therapy of primary hypertension disease curative effect is distinct, and fewer side effects, clinical medicat