口服抗血小板药物用于治疗冠心病的临床效果观察.docVIP

精品论文 参考文献 口服抗血小板药物用于治疗冠心病的临床效果观察 赤峰学院附属医院 赤峰024005 摘要：目的：探究口服抗血小板药物用于治疗冠心病的临床疗效。方法：将于2013年5月至2014年12月在我院接受治疗的冠心病患者98例作为研究对象，并随机分为对照组和实验组各49例。对照组和实验组均口服阿司匹林进行常规治疗，对照组患者在常规治疗基础上再口服氢氯吡格雷片进行治疗；实验组患者在常规治疗的基础上再口服普拉格雷片口服进行治疗。治疗期间观察两组患者的临床疗效和可能出现的不良反应，以及血小板聚集率和血小板反应指数。结果：与对照组相比，实验组患者中治疗有效率显著升高，且不良反应发生率显著降低低（P＜0.05）；同时实验组血小板聚集率和血小板反应指数的改善情况与对照组相比具有显著性（P＜0.05）。结论：口服抗血小板药物对于冠心病患者具有更好的临床疗效，并且不良反应发生率低，在临床上值得推广。 关键词：冠心病；抗血小板药；阿司匹林；氢氯吡格雷片；普拉格雷片 【中图分类号】R914【文献标识码】A【文章编号】1001-5213(2016)08-0244-01 Abstract: Objective: To explore the clinical efficacy of oral anti platelet drugs in the treatment of coronary heart disease. Methods: 98 cases of coronary heart disease patients treated in our hospital from May 2013 to December 2014 were randomly divided into control group and experimental group with 49 cases in each group. The control group and the experimental group were oral aspirin for conventional treatment, the control group patients in conventional therapy and oral clopidogrel tablets for treatment; patients in the experimental group on the basis of routine treatment again oral prasugrel tablets treatment. Clinical efficacy and adverse reactions of the two groups were observed during the treatment, as well as platelet aggregation rate and platelet response index. Results: compared with the control group, patients in the experimental group in the effective rate of treatment was significantly increased, and adverse reactions occurred were significantly lower (P lt; 0.05). The group, the platelet aggregation rate and the platelet reactivity index to improve the situation and control group was significant (P lt; 0.05) compared. Conclusion: oral anti platelet drugs in patients with coronary heart disease has better clinical efficacy, and adverse reaction rate is low, it is worth popularizing in clinic. Keywords: coronary heart disease; antiplatelet drugs; aspirin; clopidogrel tablets; prasugrel tablets 冠状动脉粥样硬化性心脏病(coronary atherosclerotic heart disease)简称为冠心病，是临床最常见的疾病之一，主要是由