2009-2016年四川省手足口病流行病学和病原学特征分析.docVIP

2009-2016年四川省手足口病流行病学和病原学特征分析 刘雅琼 袁伟 吕强 四川省疾病预防控制中心急性传染病预防控制所肠道科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的 分析2009-2016年四川省手足口病的流行特征, 为手足口病的科学防治提供依据。方法从《疾病监测信息报告管理系统》中获取2009-2016年所有手足口病个案资料, 采用描述性流行病学方法分析。结果 2009-2016年四川省累计报告手足口病467 714例, 年均发病率为71.95/10万, 累计报告重症病例4 110例, 占报告病例总数的0.88%, 死亡病例161例, 总病死率为0.034%。发病年龄主要分布在≤5岁儿童, 占病例总数的93.04%;男女性别比为1.49∶1。病例以散居儿童为主, 占病例总数的63.34%。全年有两个发病高峰, 春夏高峰为47月, 秋冬高峰为11月。重症病例多发于47月。地区间发病水平差异明显, 成都平原及周边地区发病率和病例数均高于全省其他地区。实验室确诊病例31 116例, 病原学构成中柯萨奇病毒A16型 (coxsackie virus A16, Cox A16) 占25.95%, 肠道病毒71型 (enterovirus type 71, EV71) 占29.27%, 其他肠道病毒占44.78%。结论四川省手足口病流行强度大、地理分布范围广、流行持续时间长, 应坚持做好病原学监测, 加强重点人群和重点地区的防控工作。 关键词： 手足口病; 流行病学; 柯萨奇病毒感染; 肠道病毒A型, 人; 作者简介：刘雅琼 (1986-) , 女, 甘肃敦煌人, 公卫医师, 硕士。主要研究方向:传染病流行病学。 作者简介：吕强, E-mail:lvqiang65@ 收稿日期：2017-04-27 Epidemiological and etiological characteristics of hand, foot and mouth disease in Sichuan Province, 2009-2016 LIU Ya-qiong YUAN Wei LV Qiang Institute for Acute Infectious diseases Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention; Abstract： Objective To analyze the epidemic characteristics of hand foot and mouth disease ( HFMD) in Sichuan Province from 2009 to 2014 and provide evidence for prevention and control. Methods A descriptive analysis was conducted by downloading the case-data of HFMD in Sichuan Province from 2009 to 2014 from the chinese national notifiable infectious disease reporting system. Results A total of 467 714 cases of HFMD were reported from 2009 to 2016, including4 110 severe cases and 161 deaths. The average annual incidence rate was 71. 95/100 000, the severe cases rate and fatality rate were 0. 88% and 0. 034%. Cases in children aged 5 or younger accounted for 93. 04%. Boys had higher incidence than girls ( 1. 49 ∶ 1) . The scattered children accounted for 63. 34%. Two peaks of incidence were observed every year, with the highest occurring between April and July and the second occurring