妊娠期糖尿病用药的安全性与有效性评价浅析.docVIP

精品论文 参考文献 妊娠期糖尿病用药的安全性与有效性评价浅析 蔡波 　　（陕西省延安市人民医院 陕西 延安 716000） 　　【摘 要】目的：比较不同药物治疗妊娠期糖尿病的安全性和有效性。方法：选取2013年3月至2015年3月期间在我院接受治疗的103例妊娠期糖尿病患者，将所有患者进行编号，根据单双号分为对照组（n=50）和治疗组（n=53）,对照组予以生物合成人胰岛素注射液治疗，治疗组予以门冬胰岛素治疗，比较两组患者的临床治疗效果。结果：治疗前，两组患者的空腹血糖、餐后2h血糖以及糖化血红蛋白等指标比较（P＞0.05），治疗后，治疗组患者的空腹血糖、餐后2h血糖以及糖化血红蛋白等指标改善情况以及胰岛素用量和血糖恢复正常的时间均优于对照组（P＜0.05），对照组低血糖发生率12%高于治疗组低血糖的发生率2%，（x2=4.154，P=0.042）。结论:应用门冬胰岛素治疗妊娠期糖尿病能有效改善血糖指标变化，安全性高，具有推广价值。 　　【关键词】门冬胰岛素；妊娠期糖尿病；安全性；有效性 　　【中图分类号】R714.255 【文献标识码】B 【文章编号】1003-5028（2015）8-0482-01 　　Analysis of the safety and effectiveness of drug use in gestational diabetes mellitus 　　Yanan Peoples Hospital of Shaanxi province Cai Bo zip code: 716000 　　【Abstract】Objective:To compare of different treatment of gestational diabetes medication safety and effectiveness.Methods:Select from March 2013 to March 2015 in our hospital treated 103 cases of gestational diabetes, all patients will be numbered, according to odd and even numbers divided into two groups (n = 50) and treatment group (n = 53 ), the control group was given biosynthetic human insulin injection therapy, treatment group received insulin aspart treatment, clinical outcomes between the two groups of patientsResults:Before treatment, the two groups of patients with fasting blood glucose, postprandial 2h plasma glucose and glycosylated hemoglobin and other indicators of comparison (Pgt; 0.05), after treatment, patients treated with fasting blood glucose, postprandial 2h plasma glucose and glycosylated hemoglobin and other indicators to improve the situation and the insulin dosage and blood sugar returned to normal time than the control group (P lt;0.05), the incidence of hypoglycemia in the control group 12% higher than the incidence of hypoglycemia treated 2%, (x2 = 4.154, P = 0.042).Conclusion:Gestational diabetes use insulin aspart improves glycemic index change is effective, safe, has promotional value. 　　【Key word】Insulin aspart; gestational diabetes; safety; effectiveness 　　妊娠期糖尿病是临床妇科