莫西沙星治疗厌氧菌感染的临床疗效观察.pdfVIP

1218 Chinese Journal of Medicinal Guide 2011 Volume 13 No.7 (Serial No.93) 莫西沙星治疗厌氧菌感染的临床疗效观察 * 陈琦,何双军,陈怡,朱长清 (上海交通大学医学院附属仁济医院急诊科,上海200127) 【 】 评价莫西沙星治疗厌氧菌感染的临床疗效。 在莫西沙星与甲硝唑治疗厌氧菌感染的临床随机对照研究中,对 摘要 目的: 方法: 250例厌氧菌感染患者的疗效作对照分析。结果:莫西沙星组和对照组有效率分别为90.3%和79.2%,耐药菌株发生率分别为0%和 2.2%,两组比较差异有统计学意义(P0.05) 。结论:莫西沙星在治疗厌氧菌感染中有显著疗效且较少产生耐药菌株。 【 】厌氧菌感染;莫西沙星; 甲硝唑;耐药菌株 关键词 【 】 R978;R378 【 】A 【 】1009-0959(2011)07-12 18-02 中图分类号 文献标识码 文章编号 Clinical Efficacy of Moxifloxacin in the Treatment of Anaerobic Infection Chen Qi, He Shuang-jun,Chen Yi,et al. (Emergency Department of Renj i Hospital,Shanghai JiaoTong University of Medicine,Shanghai 200127,China) 【 】 To evaluate the clinical efficacy of moxifloxacin in the treatment of anaerobic infection. The clini- ABSTRACT Objective: Methods: cal efficacy for anaerobic bacteria infection was analyzed in a randomized,cotrolled clinical trial of moxifloxacin compared with metroni- dazole therapy in the treatment of 250 cases.Results:The efficacy rate was 90.3% in moxifloxacin group and 79.2% in the control group. The incidence of drug-resistant strains in the two groups was 0% and 2.2%,respectively.The difference between groups was statistically significant(P0.05).Conclusion:The use of moxifloxacin in the treatment of anaerobic infection revealed increased efficacy and lower inci- dence of drug-resistant strains. 【 】Anaerobic infection;Moxifloxacin;Metronidazole;Drug resistance KEY WORDS 抗生素的耐药性问