核医学 肿瘤与炎症-20151012.ppt

临床意义 FDG PET/CT对胰腺癌的诊断、临床分期、疗效评价、检测术后肿瘤复发及判断预后具有重要的临床意义。 临床分析 由于糖尿病、高血糖、急慢性胰腺炎、活动性胰腺结核可出现假阳性及假阴性。 肝 癌 表11.FDG PET/CT鉴别肝内良恶性肿瘤价值 肝内病灶 例数 符合率％ 腺癌及肉瘤肝转移 66 100（66/66） 胆管癌 8 100(8/8) 肝细胞癌 23 70(16/23) Table 7.Detection of primary breast cancer Author Cases Tech Sens Spec Acc Hoh 26 PET MAMMO 85% 70% 86% 57% 85% 67% Niewag 11 PET 91% 100% 95% Dahdashti 32 PET 88% 100% 91% Wang 23 PET 93% 91% 100% Total 92 PET 89% 94% 93% Table 8.Detection of axillary involvement of breast cancer Author Cases Tech Sens Spec Acc Wahl 8 PET 83% 100% 88% Crowe 28 PET 90% 100% 95% Jacobs 16 PET 100% 93% 94% Scheidhauer 9 PET MAMMO 89% 72% 93% 94% Utech 124 PET 100% 64% Crippa 25 PET 85% 85% Wang 23 PET 80% 90% 87% Total 233 PET 90% 89% 92% 淋 巴 瘤 Table 9.Detection of lymphoma Author Cases Tech Sens Spec Acc Henrich 11 PET CT 100% 82% Zanzi 5 PET 100% Newman 16 PET CT 100% 91% 100% 100% 100% 91% Schonberger 17 PET 100% Rodriguez 23 PET 100% Schonberger 16 PET 94% Total 88 PET 99% 100% 96% 治 疗 前 治 疗 后 消 化 道 肿 瘤 胃 癌 食 管 癌 治疗前 治疗后 大 肠 癌 Table 10.Differentiation of locally recurrent colorectal tumor vs scar Author Cases Tech Sens Spec Acc Schlay 18 PET IS 92% 40% 100% 50% 94% 43% Strauss 29 PET 95% 100% 97% Engenhart 21 PET 95% Ito 15 PET MRI 100% 91% 100% 100% Pounds 33 PET 96% 53% Schonberger 76 PET CT 93% 60% 97% 79% 95% 68% Total 192 PET 95% 99% 97% 胰 腺 癌 Table 10.Detection of locally pancreatic cancer Author Cases Tech Sens Spec Acc Bares 47 PET 94% 100% 96% Stollfuss 43 PET CT 95% 80% 90% 74% 95% 78% Stollfuss 44 PET CT ERCP 93% 83 % 93 % 87% 78 % 91 % 90% 81% 92 % Inokuma 25 PET Tl-201 96% 64% Higashi 54 333 PET CT US EUS 95% 97% 90 % 91 % 85% 93 % 62 % 67 % 93 % 80 % 83 % 84 % Total 210 PET 95% 91% 94% 局限性 小病灶难以检出 糖尿病的影响 血糖水平低于130mg/dl患者检出率86％。 血糖水平超过130mg/dl患者检出率42％。 急慢性胰腺炎、活动性胰腺结核 延迟显像可能对鉴别胰腺癌和胰腺炎有一定的帮助。 Table1.Detection of primary lung cancer Author Cases Tech Sens Spec Acc Gupta 61 PET 93% 85% 92% Wahl 23 PET CT 100% 100%