神经病学精品教学：EPILEPSY.pptxVIP

EPILEPSYOutlineDefinition (epilepsy and seizure)classification and clinical manifestationEEG in Epilepsydiagnosis (three steps, differential diagnosis, common causes of seizures )Evaluation of a new seizure disorder TreatmentStatus epilepticusManagement of Convulsive Status EpilepticusSeizurea transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brainEpilepsyEpilepsy may be defined as an intermittent derangement of the nervous system due to “a sudden, excessive and disorderly discharge of cerebral neurons”Epilepsy-2005(ILAE, IBE)a disorder of the brain characterized by an enduring predisposition to generate epileptic seizure and by the neurobiologic, cognitive, psychological, and social consequences of this condition, requires the occurrence of at least one epileptic seizureClinical diversity: unconsciousness, alteration of perception or psychic function, convulsive movements, sensation.Characteristic recurrent and paroxysmal loss of consciousness is not essential OutlineDefinition (epilepsy and seizure)Etiologyclassification and clinical manifestationEEG in Epilepsydiagnosis (three steps, differential diagnosis, common causes of seizures )Evaluation of a new seizure disorder TreatmentStatus epilepticusManagement of Convulsive Status EpilepticusEtiologyInstead of the terms idiopathic, symptomatic, and cryptogenic, the following three terms and their associated concepts are recommended: Genetic, Structural/metabolic, Unknown causeGenetic: The concept of genetic epilepsy is that the epilepsy is the direct result of a known or presumed genetic defect(s) in which seizures are the core symptom of the disorder .Structural/metabolicThere is a distinct other structural or metabolic condition or disease that has been demonstrated to be associated with a substantially increased risk of developing. Structural lesions of course include acquired disorders such as stroke, trauma, and infection.neurologic disorders Stroke