尿路感染病原菌分布及耐药性检测.PDFVIP

9·82 · Chin J Nosocomiol Vol. 13 No. 10 2003 ·论 　著· 尿路感染病原菌分布及耐药性检测 喻 　华 , 刘 　华 , 颜英俊 , 周忠华 , 传良敏 ( 四川省人民医院 , 四川 成都 610072) 摘要 : 目的 　探讨尿路感染病原菌的分布及耐药性特征 , 为临床合理选用抗生素、控制医院感染提供依据。 方法 　收集我院尿路感染患者标本中分离的 151 株病原菌进行鉴定 , 同时对 G- 杆菌进行 ESBLs 的检测 ,肠球菌 ( ) 属进行氨基糖苷类高水平耐药 HLAR 的筛选。结果 　尿路感染病原菌分布占前几位的细菌为大肠埃希菌 5364 % 、肠球菌属 927 % 、凝固酶阴性葡萄球菌 7 95 % 、假单胞菌 596 % ; 产 ESBLs 大肠埃希菌的检出率为 1358 % ,产 ESBLs 肺炎克雷伯菌的检出率为 1667 % ,HLAR 肠球菌属检出率为 5714 % 。结论 　重视尿路感染 病原菌耐药性检测 ,对控制医院感染、合理使用抗生素十分重要。 关键词 : 尿路感染 ; 病原菌 ; 耐药性 中图分类号: R691. 3 　　文献标识码 : A 　　文章编号 : (2003) Distribution of Pathogens and Resistance Detection in Urinary Infection YU Hua , L IU Hua , YAN Yingjun , ZHOU Zhon ghua , CHUAN Liangmin ( People ′s Hospital of S ichuan Province , Chengdu 610072 , China) Abstract : OBJECTIVE To determine distribution of pathogens and resistance characteristic and to provide basis for clinicians to select antibiotics correctly and control nosocomial infection. METHODS A total of 151 strains of pathogens were identified. ESBLsproducing G- bacteria were detected and highlevel aminoglycoside resistance in Enterococcus (HLAR) were screened. RESULTS Among 151 strains , 5364 % Escherichia coli , 927 % Enterococcus , 795 % coagulase negative S taphylococcus and 596 % Pseudomonas were detected. 1358 % E . coli and 1667 % Klebsiella pneumoniae produced ESBLs. HLARproducing Enterococcus was 57 14 %. CONCL USIONS Much attention should be paid to resistance detection in urinary infection. It is important to control nosocomial infection and select antibiotics correctly