性别与2型糖尿病合并骨质疏松患者骨密度改变的相关性研究.docVIP

精品论文 参考文献 性别与2型糖尿病合并骨质疏松患者骨密度改变的相关性研究 付彩雯 朱晓荣 吴艳（通讯作者） （四川省遂宁市中心医院内分泌科 四川 遂宁 629000） 【摘要】 目的：探讨性别与2型糖尿病(type 2 diabetes, T2DM)合并骨质疏松(osteoporosis, OP)患者骨密度(Bone mineral density, BMD)改变的相关关系。方法：在四川省遂宁市中心医院门诊及住院的T2DM合并OP患者100例作为研究对象，采用双能X线骨密度测量仪测量正位腰椎和左侧股骨颈的骨密度值，比较不同性别患者骨密度之间的差异。结果：本研究共纳入符合条件的T2DM合并OP患者100例，其中男性46例，女性54例；平均年龄55.78plusmn;8.74岁；平均BMI为25.81plusmn;4.27。两组T2DM患者在平均年龄、平均体重指数、基础疾病情况、饮酒史方面差异均无统计学意义（Pgt;0.05），具有可比性，而吸烟患者的比例男性明显多于女性患者。女性T2DM合并OP患者的腰椎、股骨颈骨密度测定值明显低于男性患者，且差异有统计学意义（Plt;0.05）。T2DM合并OP患者的腰椎BMD、股骨颈BMD均与性别呈负相关关系（Plt;0.001）。结论：女性患者可能会增加T2DM继发OP的发病风险，而定期保持营养均衡、多摄入含钙的食物是预防的治疗骨质疏松有效手段之一。 【关键词】 2型糖尿病；骨质疏松症；并发症；性别因素 【中图分类号】R587.1 【文献标识码】A 【文章编号】2095-1752（2015）32-0115-02 Study on the correlation of bone mineral density in patients with type 2 diabetes mellitus complicated with osteoporosis Fu Cai wenZhu Xiao rong Wu Yan(Endocrinology Department Suining Central Hospital Suining 629000 Sichuan China) 【Abstract】Objective To Investigate the gender and type 2 diabetes (T2DM) merger osteoporosis (OP) BMD patients (BMD) changes in correlation. Methods Select 100 cases type 2 diabetes merger osteoporosis in Suining Central Hospital as the research object, Using X-ray bone density measurement of bone mineral density to measure the lumbar spine and left femoral neck value dual energy. Results This study included 100 patients with T2DM combined with OP, including 46 males and 55.78 females, with an average age of 54plusmn;8.74 years old, with an average of 25.81plusmn;4.27. The two groups of patients with T2DM in average age, average body mass index, basic disease, drinking history differences were not statistically significant (Pgt;0.05), with can be compared, and smoking were the proportion of male was significantly higher than that of the female patients. The BMD of lumbar spine and femoral neck in female patients with T2DM combined with OP was significantly lower than that of male p