探讨他汀类药物在慢性心力衰竭治疗中的临床观察.docVIP

精品论文 参考文献 探讨他汀类药物在慢性心力衰竭治疗中的临床观察 大庆市人民医院 163316 摘要：目的：研究分析慢性心力衰竭的治疗中使用他汀类药物的临床观察。方法：此次研究的对象是选取在2013年3月-2015年3月中我院收治的128例慢性心力衰竭患者，将其临床资料进行回顾性分析，并随机将参与实验的慢性心力衰竭患者分为实验组与对照组。其中实验组中患者有72例，对照组患者有56例。对照组患者采用常规药物治疗，实验组患者在常规治疗的基础上联合他汀类药物进行治疗。比较两组患者的心功能分级、左心室射血分数以及LVESD、LVEDD、LVEF及NT-pro BNP变化差异。结果：对照组患者治疗后的心功能分级低于实验组中的患者。实验组中患者左心室射血分数明显高于对照组中的患者。实验组中的72例慢性心力衰竭患者的LVEF变化及NT-pro BNP水平变化优于对照组中的56例慢性心力衰竭患者。结论：治疗慢性心力衰竭中常规治疗联合他汀类药物的临床效果优异，对患者的心功能有明显的改善。 　　关键词：他汀类药物 心力衰竭 心功能改善 [Abstract] Objective：To study the clinical observation of the use of statins in the treatment of chronic heart failure. Methods：the study object is selected in March 2013 and 2015，3 months in our hospital from 128 cases of patients with chronic heart failure，their clinical data were retrospectively analyzed，and random will be involved in the chronic heart failure patients divided into experimental group and control group. There were 72 cases in the experimental group and 56 cases in the control group. Patients in the control group were treated with routine drug therapy，and the experimental group were treated with combination of statins on the basis of conventional therapy. The changes of cardiac function，left ventricular ejection fraction，LVESD，LVEDD，LVEF and BNP NT-pro were compared between the two groups. Results：the heart function of the control group after treatment was lower than that in the experimental group. The left ventricular ejection fraction in the experimental group was significantly higher than that in the control group. The change of LVEF and BNP NT-pro in 72 patients with chronic heart failure in the experimental group was better than that in the control group and 56 patients with chronic heart failure. Conclusion：the clinical effect of conventional therapy combined with statins in the treatment of chronic heart failure is excellent，and the cardiac function of the patients is obviously improved. [Key words] statins heart failure cardiac function improvement 随着社会的发展，由于一些不良饮食以及生