泮托拉唑与奥曲肽治疗上消化道出血的临床分析.docVIP

精品论文 参考文献 泮托拉唑与奥曲肽治疗上消化道出血的临床分析 （南部县人民医院 四川南充 637300） 　　【摘要】目的：分析泮托拉唑与奥曲肽治疗上消化道出血的临床效果。方法：选取我院最近几年收治的上消化道出血50例作为观察组，并将同期收治的50例上消化道出血患者设为对照组，予以对照组泮托拉唑治疗，予以观察组泮托拉唑与奥曲肽治疗，对比两组的临床疗效。结果：观察组总有效率98%明显高于对照组的80%，差异有统计学意义（Plt;0.05）。观察组不良反应发生率8%显著低于对照组的28%，差异有统计学意义（Plt;0.05）。结论：泮托拉唑联合奥曲肽治疗上消化道出血，效果明显，安全性高，值得推广。 　　【关键词】泮托拉唑与奥曲肽；上消化道出血；临床效果 　　【中图分类号】R573.2 【文献标识码】A 【文章编号】1007-8231（2016）17-0013-02 　　【Abstract】Objective To analyze the clinical effect of digestive tract hemorrhage of pantoprazole and octreotide treatment.Methods in our hospital in recent years were hemorrhage of upper digestive tract in 50 cases as the observation group,and will be admitted in the same period of 50 cases of patients with upper digestive tract hemorrhage were set as control group,to be in control group of pantoprazole in the treatment of,be observed pantoprazole group were treated with octreotide,compared to two groups of clinical effect.Results The total effective rate of the observation group was 80% higher than that of the control group(98%),and the difference was statistically significant(Plt;0.05).The incidence of adverse reactions in the observation group 8% was significantly lower than that of the control group (28%),the difference was statistically significant (Plt;0.05).Conclusion Bleeding, pantoprazole combined with octreotide in the treatment of upper digestive effect,high safety, worthy of promotion. 　　【Key words】Octreotide and pantoprazole;Upper gastrointestinal bleeding;Clinical effect 　　上消化道出血为内科常见病之一，发病率高，且病因十分复杂、病情变化迅速，造成出血性休克的几率很高，危及患者的身心健康。奥曲肽是由人工合成的长效生长激素释放抑制剂，可有效抑制多种消化液与消化道激素的分泌，降低肝门静脉压并减少消化道内血流量，止血迅速[1]。为了分析泮托拉唑与奥曲肽治疗上消化道出血的临床效果，本文对我院50例采用泮托拉唑与奥曲肽治疗的上消化道出血患者作出研究，现将结果报道如下。 　　1.资料与方法 　　1.1 一般资料 　　选取2013年1月至2015年2月我院收治的50例上消化道出血患者作为观察组，其中男29例，女21例；年龄年龄16～84岁，平均年龄（36.55plusmn;4.32）岁；按出血程度：轻度22例，中度16例，重度12例。同时将同期收治的50例上消化道出血患者设为对照组，其中男28例，女22例；年龄年龄17～85岁，平均年龄（36.76plusmn;4.56）岁；按出血程度：轻度23例，中度14例，重度13例。两组患者的额一般资料经对比，差异无统计学意义（P＞0.05），具有可比性。 　　1