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Clinicalstudyofaorticelasticityincoronaryheartdisease
evaluatedbyPulsedWaveDopplerTissueImaging.
Tutor:Prof Guangxuefeng
Postgraduate:Ma Min
DepartmentofCardiology,SecondAffiliatedHospital,KunmingMedicalCollege,
Kunming650101
Abstract
Objective:todetermineclinicalvalueofpulsedwaveDopplertissueimaging
(PW-DTI)inevaluatingaorticelasticiyt incoronaryheartdisease.Methods:
M-modeechocardiographyandpulsedwaveDopplertissueimaging(PW-DTI)were
appliedtoexamine34patientswithcoronaryheartdisease(meanage62i-10years,
20male,14female),and30patientswithoutcoronaryheartdisease(meanage60士7
years,14male,16female)evaluatedbyangiograp坷,andpatientswithanyone
coronaryarterylesionofatleast50%lesionwereclassifiedasthepatientswith
coronaryheartdisease. Aorticupperwallvelocities(includingSwave,Ewaveand
Awavecm/sec),aorticstiffnessindexandaorticdistensibiliytweredeterminedthat
reflectaorticelasticity.Aorticsystolicdiameter(Ds)anddiastolicdiameter(Dd)were
measuredbyM-modeechocardiographyandaorticupperwalltissuevelocitieswere
measuredbyPW-DTI3cmabovetheaorticvalve.Lateralmitralannulustissue
velocities(includingSwave,EwaveandA wave)werealsomeasuredby
PW-DTI.Formulaforaorticstiffnessindexis:
(1nSBP-1nDBP)XDd/(Ds-Dd),formulaforaorticrootdistensibiliyt is:2X
(Ds-Dd)/PPXDd(cmzdynes1),andPPstandsforpulsepressure.Results:Aortic
upperwallSwavevelocitywaslowerincoronaryheartdiseasepatients8.2士
2.4(cm/sec)vs11.7士3.6(cm/sec),P0.05;aorticstiffnessindexwashigherin
coronaryheartdiseasepatients14.99士11.05vs11.22士7.01,P0.05.Logistic
analysisresultsdemonstratedthedifferencesofaorticupperwallSwavevelociyt,
aorticstiffnessindexbetweenthetwogroupsweresignificantafteradjustedfor
coronaryheartdiseaseriskfactorsandthe factorswhichaffectedbyheartfunction.
(OR=0.92,P=0.001;OR=1.11,P=0.000;respectively).Afteradjustedforcoronary
heartdiseaseriskfactorsandthe factorswhichaffectedbyheartfuncti
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