脉冲波多普勒组织成像评价冠心病患者主动脉弹性的临床研讨.pdfVIP

脉冲波多普勒组织成像评价冠心病患者主动脉弹性的临床研讨.pdf

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Clinicalstudyofaorticelasticityincoronaryheartdisease evaluatedbyPulsedWaveDopplerTissueImaging. Tutor:Prof Guangxuefeng Postgraduate:Ma Min DepartmentofCardiology,SecondAffiliatedHospital,KunmingMedicalCollege, Kunming650101 Abstract Objective:todetermineclinicalvalueofpulsedwaveDopplertissueimaging (PW-DTI)inevaluatingaorticelasticiyt incoronaryheartdisease.Methods: M-modeechocardiographyandpulsedwaveDopplertissueimaging(PW-DTI)were appliedtoexamine34patientswithcoronaryheartdisease(meanage62i-10years, 20male,14female),and30patientswithoutcoronaryheartdisease(meanage60士7 years,14male,16female)evaluatedbyangiograp坷,andpatientswithanyone coronaryarterylesionofatleast50%lesionwereclassifiedasthepatientswith coronaryheartdisease. Aorticupperwallvelocities(includingSwave,Ewaveand Awavecm/sec),aorticstiffnessindexandaorticdistensibiliytweredeterminedthat reflectaorticelasticity.Aorticsystolicdiameter(Ds)anddiastolicdiameter(Dd)were measuredbyM-modeechocardiographyandaorticupperwalltissuevelocitieswere measuredbyPW-DTI3cmabovetheaorticvalve.Lateralmitralannulustissue velocities(includingSwave,EwaveandA wave)werealsomeasuredby PW-DTI.Formulaforaorticstiffnessindexis: (1nSBP-1nDBP)XDd/(Ds-Dd),formulaforaorticrootdistensibiliyt is:2X (Ds-Dd)/PPXDd(cmzdynes1),andPPstandsforpulsepressure.Results:Aortic upperwallSwavevelocitywaslowerincoronaryheartdiseasepatients8.2士 2.4(cm/sec)vs11.7士3.6(cm/sec),P0.05;aorticstiffnessindexwashigherin coronaryheartdiseasepatients14.99士11.05vs11.22士7.01,P0.05.Logistic analysisresultsdemonstratedthedifferencesofaorticupperwallSwavevelociyt, aorticstiffnessindexbetweenthetwogroupsweresignificantafteradjustedfor coronaryheartdiseaseriskfactorsandthe factorswhichaffectedbyheartfunction. (OR=0.92,P=0.001;OR=1.11,P=0.000;respectively).Afteradjustedforcoronary heartdiseaseriskfactorsandthe factorswhichaffectedbyheartfuncti

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