溴隐亭联合克罗米芬治疗无排卵型高泌乳素血症疗效观察.docVIP

精品论文 参考文献 溴隐亭联合克罗米芬治疗无排卵型高泌乳素血症疗效观察 李晓珲 　　（四川省宜宾市第一人民医院妇科 四川 宜宾 644000） 　　【摘 要】目的：探讨溴隐亭联合克罗米芬治疗无排卵型高泌乳素血症的临床疗效。方法：回顾分析本院门诊就诊的已明确诊断并经溴隐亭治疗6月的仍无排卵型高泌乳素血症51例，根据治疗方案不同，随机分成溴隐亭组（n=26），单用溴隐亭1.25-2.5mg/d维持。联合用药组（n=25）溴隐亭1.25-2.5mg/d维持治疗，于月经的3-5天加用克罗米芬50-100mg/d口服，连用5天。两组疗程均为6月。结果：溴隐亭维持治疗组月经量少且周期不规律者11例，月经量及周期正常者15例，无排卵14例，有排卵12例。联合用药组，月经量少且周期不规律者4例，月经量及周期正常者21例，无排卵者3例，有排卵者22例。结论：对无排卵型高泌乳素血症患者，单用溴隐亭，可降低血PRL 水平，但月经恢复情况及排卵不理想，联合克罗米芬对恢复正常月经及排卵疗效较好。 　　【关键词】高泌乳素血症；溴隐亭；克罗米芬；治疗 　　【中图分类号】R588.6 【文献标识码】A 【文章编号】1004-6194（2015）01-0068-02 　　Bromocriptine combined with clomiphene in treatment of anovulatory hyperprolactinemia Clinical Observation 　　Li Xiaohui Department of Gynecology， The First Peoples Hospital of Yibin City , Sichuan Province 644000 　　【Abstract】Objective：To investigate bromocriptine combined with clomiphene in treatment of hyperprolactinemia anovulatory clinical efficacy . Methods： Retrospective analysis of 51 cases of patients with hyperprolactinemia in out-patient department of gynecology were treated by bromocriptine for 6 months, depending on the treatment plan were randomly divided into the bromocriptine group ( n = 26 ) , single bromocriptine 1.25 - 2.5mg / d to maintain ;The combined treatment group ( n = 25 ) , bromocriptine 1.25 - 2.5mg / d maintenance therapy , In the third to five days of the menstrual cycle plus clomiphene 50-100 mg / d orally for 5 days . Were treated for 6 months . Results：bromocriptine goup: menstrual volume less and irregular menstrual cycles were 11 cases, normal menstrual volume and normal cycle were 15 cases ;anovulation were 14 cases , there were 12 cases of ovulation . The combined treatment group , menstrual volume less and irregular menstrual cycles were 4 cases , normal menstrual volume and normal cycle were 21 cases ; anovulation were 3 cases , there were 22 cases of ovulation. Conclusion：patients with anovulatory hyperprolactinemia alone were used bromocriptine, can reduce levels of serum PRL , but recovery of me