生长抑素与泮托拉唑钠治疗重症急性胰腺炎的临床效果观察.docVIP

精品论文 参考文献 生长抑素与泮托拉唑钠治疗重症急性胰腺炎的临床效果观察 南京军区福州总医院急诊科 【摘 要】目的：观察评价生长抑素与泮托拉唑钠治疗重症急性胰腺炎（Severe Acute Pancreatitis，SAP）的临床效果。方法：2014年2月～2016年3月，收治SAP患者82例，均接受常规治疗，给予泮托拉唑钠治疗35例纳入对照组，给予泮托拉唑钠联合生长抑素治疗47例纳入观察组，对比相关指标。结果：3日后，观察组与对照组AMY、尿TAP水平低于治疗前，观察组低于对照组，观察组与对照组CRP低于治疗前，差异具有统计学意义（P＜0.05）；观察组腹痛缓解时间、淀粉酶恢复时间、平均住院日低于对照组，差异具有统计学意义（P＜0.05）；观察组与对照组并发症发生率、转手术率、死亡率差异无统计学意义（P＞0.05）。结论：生长抑素联合泮托拉唑钠治疗SAP疗效较好，可缩短病程，稳定病情，但并不能降低并发症发生率、手术率与死亡率。 【关键词】急性胰腺炎；生长抑素；泮托拉唑 [Abstract]Objective：To observe and evaluate the growth of somatostatin（生长抑素）and pantoprazole sodium in the treatment of severe acute pancreatitis clinical effect.Methods：February 2014 to 2016 in March，patients with SAP were treated 82 cases received routine treatment，semi pantoprazole sodium was given the treatment of 35 cases included in the control group were given semi pantoprazole sodium combined with 生长抑素 in the treatment of 47 cases were included in the observation group，comparison of relevant indicators.Results：Three days later，the observation group and the control group of Amy，urinary tap levels were lower than the treatment before，the observation group than in the control group，observation group and control group CRP lower than that before treatment，the difference is statistically significant（P lt; 0.05）；observation group abdominal pain relief time，amylase recovery time，average hospitalization days was lower than that in control group，and the difference is statistically significant（P lt; 0.05）；observation group and the control group，the incidence of complications，operation rate and mortality differences without statistical significance（P gt; 0.05）.Conclusion：endostatin combined with pantoprazole sodium in the treatment of SAP effect of growth is good，can shorten the course of disease，stable condition，but did not reduce the complications Incidence rate，operation rate and mortality rate. [Key words]acute pancreatitis；somatostatin；- prazole 重症急性胰腺炎是急性胰腺炎重症化疾病，是临床常见病，约占急性胰腺炎的10%～