益气化湿法联合强的松治疗重症肌无力的临床研究.docVIP

精品论文 参考文献 益气化湿法联合强的松治疗重症肌无力的临床研究 徐向青 蔺通通 　　（山东中医药大学附属医院脑病科 山东 济南 250011） 　　【摘 要】目的：观察益气化湿法联合强的松治疗重症肌无力的临床疗效。方法：将符合纳入标准的60例重症肌无力（Ⅲ型）患者随机分为治疗组和对照组，治疗组给予益气化湿方联合强的松，对照组给予强的松，疗程均为12周。观察治疗前后的QMG评分、强的松服用剂量及不良反应。结果：治疗后两组QMG量表评分比较差异有统计学意义(Plt;0.05 )，说明治疗组临床症状的改善优于对照组;治疗后两组强的松服用剂量总分比较差异有统计学意义(Plt;0.05 )，说明治疗组对强的松剂量的减量优于对照组，且不良反应较少。结论：益气化湿法联合强的松治疗MG方案不仅可以改善患者的QMG评分，还可以降低患者的激素服用剂量，且不良反应少，说明益气祛化湿法联合强的松治疗重症肌无力是一种安全有效的方法。 　　【关键词】重症肌无力；益气化湿法；强的松；临床研究 　　【中图分类号】R21 【文献标识码】B 【文章编号】1003-5028（2015）8-0428-02 　　【Abstract】Objective To observe yiqi huashi method combined prednisone clinical curative effect for the treatment of myasthenia gravis.Method Will be included in the standard of 60 patients with myasthenia gravis (Ⅲ type) were randomly divided into treatment group and control group, treatment group given good gasification wet method in combination with prednisone, control group for prednisone, a course of 12 weeks.Respectively before and after the treatment of patients with marks quantitative myasthenia gravis (QMG) table, prednisone doses of questionnaire investigation, observation QMG score before and after the treatment, stop taking reduction of prednisone dose. Results After treatment the QMG rating scale is similar between the two groups have statistical significance (P lt; 0.05), the treatment group in improving clinical symptoms is better than the control group; Prednisone doses scores more similar between the two groups after treatment was statistically significant (P lt; 0.05), the treatment group of prednisone dose reduction is better than that of control group, and found lesser adverse reactions.than control group .Conclusion Qiqi huashi method can not only improve the patients QMG score, can also reduce the hormone doses of patients, and lesser adverse reaction, yiqi huashi method for joint prednisone treatment of myasthenia gravis is a safe and effective method. 　　【Key words】Myasthenia gravis; Good gasification wet; Prednisone; Clinical research 　　重症肌无力（MG）是