硫酸阿奇霉素治疗小儿支原体肺炎的疗效及对患儿肝功能的影响.docVIP

精品论文 参考文献 硫酸阿奇霉素治疗小儿支原体肺炎的疗效及对患儿肝功能的影响 柳州市柳铁中心医院 广西柳州 545007 　　【摘 要】目的 探讨硫酸阿奇霉素治疗小儿支原体肺炎的疗效及对患儿肝功能的影响。方法 选取本院于2014年1月-2016年5月收治的122例支原体肺炎患儿作为实验对象，随机分为对照组和观察组，各61例。两组均行常规治疗，对照组病患行头孢三代治疗，观察组行头孢三代联合硫酸阿奇霉素治疗，观察两组病患的治疗效果。结果 观察组总有效率（98.36%）明显优于对照组（86.89%），观察组不良反应发生率（4.92%）明显小于对照组（16.39%），差异具有统计学意义（Plt;0.05）；两组患儿用药前检测肝功能均正常，用药后，部分病患ALT异常，组间比较差异显著（Plt;0.05）。结论 硫酸阿奇霉素治疗小儿支原体肺炎的疗效显著，具有起效快、不良反应少、疗效好等特点，对患儿肝功能损害较小，是较为理想的治疗小儿支原体肺炎的药物。 　　【关键词】硫酸阿奇霉素；肝功能；疗效；小儿支原体肺炎 　　The efficacy of azithromycin sulfate treatment of children with mycoplasma pneumonia and its impact on patients liver function 　　Li Huifen 　　（Liuzhou Liuzhou Railway Central Hospital，Liuzhou Guangxi 545007） 　　[Abstract] Objective To expore the efficacy of azithromycin sulfate treatment of children with mycoplasma pneumonia and its impact on patients liver function.Methods 122 cases of mycoplasma pneumonia treated in our hospital in January 2014 - May 2016 were selected as xperimental subjects，were randomly divided into control group and observation group，61 cases each. Two groups were given conventional treatment，patients in the control group were given third generation cephalosporin treatment，the observation group were given third generation cephalosporin combined azithromycin sulfate for treatment，the therapeutic effect of the two groups of patients were observed. Results Observation group total effective rate（98.36%）was significant better than the control group（86.89%），Observation group adverse reaction rates（4.92%）was significantly lower than the control group（16.39%），the difference was statistically significant（Plt;0.05）；Two groups of children before treatment to check liver function were normal，after treatment，ALT of part of patients was abnormal，difference between groups was significant（P lt;0.05）. Conclusion Efficacy of a azithromycin sulfate treatment of children with mycoplasma pneumonia is significant，with rapid onset，fewer adverse reactions，efficacy and other characteristics，impaired liver function for