病理学生殖系统和乳腺疾病2015医学课件.ppt

* * 子宫颈原位癌累及腺体，异型细胞占据宫颈全层并累及腺体，但基膜完整。CIN iii * * acetowhite changes A pathologist can tell on pap smear, and confirm on biopsy; the latter is more precise as long as you get the right spot (which is made easier by the fact that CIN doesnt stain as well as normal cervix with iodine (Schiller test), and will turn white on application of acetic acid, the acetowhite test). Future pathologists: Staining pap smears routinely for p16INK?4a, whichis strongly overexpressed in premalignant / malignant cervical epithelial cells, may soon be routine as a way to help screeners. Though not specific, it see