舌下含服粉尘螨滴剂对变应性鼻炎患者的疗效分析.docVIP

精品论文 参考文献 舌下含服粉尘螨滴剂对变应性鼻炎患者的疗效分析 陈郁敏 　　（南平市第一医院耳鼻咽喉科 福建 南平 353100） 　　【摘要】 目的：评估舌下含服标准化粉尘螨变应原制剂对变应性鼻炎患者的疗效。方法：采用治疗前后的自身对照，回顾性的分析了来我科室就诊并接受舌下特异性免疫治疗（SLIT）治疗的65例尘螨过敏的变应性鼻炎患者。比较了其治疗前与治疗3个月、6个月、12个月后的症状评分和药物评分，以评价其疗效。用SPSS21.0软件对统计数据进行分析处理。结果：与治疗前相比，变应性鼻炎患者经SLIT治疗3个月、6个月、12个月后其症状评分得到显著的改善，P均＜0.05。与治疗前相比，变应性鼻炎患者经SLIT治疗3个月、6个月、12个月后其用药评分得到明显的降低，P均＜0.05。结论：舌下含服粉尘螨滴剂能明显缓解变应性鼻炎患者的症状，也能减少患者的抗过敏药物的使用。 　　【关键词】舌下特异性免疫治疗；变应性鼻炎；疗效 　　【中图分类号】R765.21 【文献标识码】A 【文章编号】2095-1752（2015）06-0109-02 　　Sublingual administering dust mites drops in patients with allergic rhinitis curative effect analysis Chen Yumin. Nanping The first hospital of Nanping city, in Fujian province, Nanping 353100, China 　　【Abstract】 Objective Evaluate sublingual administering standardized dust mite allergen preparation in patients with allergic rhinitis curative effect. Methods Use before and after treatment of self-reflection, I department were retrospectively analyzed to see a doctor and accept the sublingual specific immunotherapy (SLIT) treatment of 65 cases of dust mites allergic patients with allergic rhinitis. Results Compared with before treatment, patients with allergic rhinitis were treated SLIT 3 months, 6 months and 12 months after the symptom scores was significantly improved, P lt; 0.05. Compared with before treatment, patients with allergic rhinitis were treated SLIT 3 months, 6 months and 12 months after the drug significantly lower score, P lt; 0.05. Conclusions Sublingual administering dust mites drops can obviously alleviate the symptoms of patients with allergic rhinitis, also can reduce the patients allergy drug use. 　　【Key words】Under the tongue specific immune therapy. Allergic rhinitis; The curative effect 　　变应性鼻炎（Allergic rhinitis，AR）发病率为10%～25%[1]。目前，临床常见的治疗方法包括避免接触过敏原、药物治疗、变应原特异性免疫治疗等[2]。变应原特异性免疫治疗（allergen specific immunotherapy，ASIT）被认为是唯一能够改变变应性疾病自然进程的治疗方法，其主要的给药途径有皮下注射和舌下含服。舌下含服特异性免疫治疗（sublingual immunotherapy ，SLIT）是一种新颖的给药方式，具有安全、方便、有效等优点，目前在