血压晨峰、动态动脉硬化指数与颈动脉内膜中层厚度相关性分析.docVIP

精品论文 参考文献 血压晨峰、动态动脉硬化指数与颈动脉内膜中层厚度相关性分析 蔡战友 　　郑州市中牟县第二人民医院，河南 郑州 451450 　　摘要：目的 探讨血压晨峰、动态动脉硬化指数与颈动脉内膜中层厚度的关系。方法 对212例入选病例监测24h动态血压和行颈动脉超声检查测量颈总动脉内-中膜厚度(carotid artery intima-media thickness．IMT)，记录各血压值，计算血压晨峰值及动态动脉硬化指数(ambulatory arterial stiffness index，AASI)。观察血压晨峰、动态动脉硬化指数与颈动脉内膜中层厚度的相关性。结果 IMT增厚组中AASI及血压晨峰均显著高于IMT正常组(P＜0.05)；血压晨峰组中AASI、IMT均显著高于非血压晨峰组(P＜0.05)；直线相关分析结果显示，血压晨峰和动态动脉硬化指数较其他因素与颈动脉内膜中层厚度的关系密切。结论 血压晨峰和动态动脉硬化指数是颈动脉内膜中层厚度的独立危险因素，且有更佳预测价值。 　　关键词：血压晨峰；动态动脉硬化指数；动脉内-中膜厚度 　　中图分类号：+ R 　　Analysis of the relationship between morningblood pressure surge,ambulatory arterial stiffness index and carotid artery intima-media thickness CAI Zhan-you.The Second Peoples Hospital of Zhongmu County,Henan Zhengzhou 451450,China. 　　[Abstract] Objective To discuss the relationship between morningblood pressure surge,ambulatory arterial stiffness index and carotid artery intima-media thickness. Methods 212 cases of selected patients with hypertension were performed 24 h ambulatory blood pressure monitoring with monitors．Duppler ultrasonography was used to measure the intima—media thickness(IMT)of carotid, and recording the blood pressure value.Finally calculated the morningblood pressure surge and ambulatory arterial stiffness index.to observe the relationship between morningblood pressure surge,ambulatory arterial stiffness index and carotid artery intima-media thickness.Results morning blood pressure surge and ambulatory arterial stiffness index were significantly higher in carotid artery intima-media thickness group compared to normal coronary artery group (P＜0.05);Compared with the nonsurge group,ambulatory arterial stiffness index and carotid artery intima-media thickness in MBPS group increased markedly(P＜0.05); Linear correlation analysis results show that the morning blood pressure peak and dynamic arteriosclerosis index than other factors closely associated with carotid intima-media thickness. Conclusion Morning blood pressure peak and dynamic arteriosclerosis ind