超声、钼钯、CT和MRI对乳腺肿块诊断的Meta分析.docVIP

精品论文 参考文献 超声、钼钯、CT和MRI对乳腺肿块诊断的Meta分析 杜典国 　　（新疆维吾尔自治区人民医院北院 新疆 乌鲁木齐 830000） 　　【摘 要】目的：探讨超声、钼钯、CT和MRI对乳腺肿块诊断的Meta分析。方法：从各中英文数据库中对乳腺肿块诊断中超声、钼钯、CT和MRI有关的文献进行检索，评价所有纳入研究的质量并将相关信息提取出来，运用Meta-disc 1.4 软件进行Meta分析。结果：MRI和超声+钼靶+CT+MRI的诊断效能均明显比B超、钼靶、CT高（Plt;0.05）；患者的平均年龄影响着超声研究间异质性来源，是否依据BI-RADS诊断标准影响着钼靶研究异质性来源，各协变量均不会影响到CT、MRI回归分析显示的研究间异质性来源。结论：超声+钼靶+CT+MRI联合对乳腺肿块具有较高的诊断价值。 　　【关键词】超声；钼靶；CT；MRI；乳腺肿块；诊断；Meta分析 　　【中图分类号】R711 【文献标识码】A 【文章编号】1004-6194（2015）01-0240-02 　　Meta-analysis of ultrasound, molybdenum, CT and MRI in the diagnosis of breast lumps 　　【Abstract】Objective：To investigate the Meta-analysis of ultrasound, molybdenum, Meta analysis of CT and MRI in the diagnosis of breast lumps. Methods：The relevant literature of ultrasound, molybdenum, CT and MRI diagnosis of breast lumps were searched from Chinese and English database, the quality of all included studies and extracted relevant information were evaluated, Meta-analysis were did by Meta-disc 1.4 software. Results：The diagnostic performance of ultrasound+mammography+CT+MRI were significantly higher than B-ultrasound, mammography, CT(P lt;0.05); ultrasound study heterogeneity among sources were affected by average age of patients, mammography study heterogeneous sources were affected by whether based on BI-RADS diagnostic criteria, CT, MRI sources of heterogeneity between studies regression analysis display were not affected by each covariate. Conclusion：Ultrasound + mammography + CT + MRI combination has high value in the diagnosis of breast lumps. 　　【Keywords】Ultrasound; mammography; CT; MRI; Breast lumps; Diagnosis; Meta Analysis 　　在乳腺肿块的诊断中，超声、钼钯、CT和MRI是临床最长采用的影像检查手段[1]，本文运用Meta分析法对以往国内外相关研究进行了分析和系统定量评价，以期将较为客观的询证医学依据提供给临床的诊断工作，现报告如下。 　　1 资料与方法 　　1.1 资料来源 　　从CNKI、CBM等数据库中检索中文文献，输入的检索词主要有乳腺肿块、超声、钼靶、CT、MRI等；从Cochrane Library、MEDLINE等数据库中检索外文文献，输入的检索词主要有breast neoplasms，ultrasound，mammography CT，MRI等[2~10]。所查文献包括学术期刊文论、学位论文等，目标对象为人类，检索年限为1998年4月到2014年1月，搜索语种为汉语与英语。为了促进文献查全率的显著提升，本文所采用的检索方式为有机结合主题词和自由词、手工和