阿奇霉素治疗慢性支气管炎合并肺部感染的临床观察.docVIP

精品论文 参考文献 阿奇霉素治疗慢性支气管炎合并肺部感染的临床观察 叶明霞 侯丽萍 王保（北京大学深圳医院 广东深圳 518000） 【摘要】目的 探究阿奇霉素治疗慢性支气管炎合并肺部感染的用药方法和治疗效果。方法 回顾分析我院在2011年6月-2012年11月期间收治的66例慢性支气管炎合并肺部感染患者的临床资料，根据患者再治疗期间所采用的用药方法不同，将66例患者随机分为对照组（33例）和观察组各（33例）两组，两组患者均行常规的镇咳、祛痰、平喘和吸氧等常规对症治疗，对照组患者在常规治疗的基础上采用阿莫西林口服治疗，观察组患者在常规治疗的基础上加用阿奇霉素治疗。比较两组患者的治疗有效率和临床并发症情况。结果 观察组患者的治疗有效率为96.97%，对照组为81.81%，两组间疗效比较差异明显，具有统计学意义，（P＜0.05），且观察组患者的不良反应发生率低于对照组，两组间比较差异明显，具有统计学意义，（P＜0.05）。结论 阿奇霉素能够有效的抑制慢性支气管炎急性发作，改善患者的肺部感染症状，疗效显著，安全性高，值得临床推广。 【关键词】 阿奇霉素 慢性支气管炎 肺部感染 阿莫西林 有效率 【中图分类号】R453 【文献标识码】A 【文章编号】2095-1752（2013）21-0149-02 Clinical observation of azithromycin in treatment of chronic bronchitis complicated by pulmonary infection Ye Mingxia, Hou Liping, Wang Bao. Peking University Shenzhen Hospital, Shenzhen, Guangdong 518000, China 【Abstract】 Objective To investigate the medications and treatment effects of azithromycin on chronic bronchitis complicated by pulmonary infection. Methods Between June 2011 and November 2012, 66 patients with chronic bronchitis complicated by pulmonary infection were admitted to the hospital used in this study. Clinical data on these patients were retrospectively analyzed. According to the medications performed during the retreatment, 66 patients were randomly divided into the control group (33 cases) and the observation group (33 cases). Conventional symptomatic treatments such as antitussive treatment, expectorant treatment, anti-asthmatic treatment, and oxygen uptake were performed for all the patients. In addition to the conventional treatments, oral amoxicillin was used for the patients in the control group, and azithromycin was used for those in the observation group. The rate of effective treatment and the occurrence of clinical complications were compared for the patients in the two groups. Results The rate of effective treatment of the observation group was 96.97%, while that of the control group was 81.81%. There was a statistical