维生素Vitamine.PPT

Chapter V Vitamine 一、the concept of Vitamine Small organic molecules essensial components for human growth and function Part 1??????? fat-soluble vitamines Common characteristics： 1、异戊二烯或异戊烯侧链 2、随脂类共同吸收 3、可在体内大量储存，易产生 中毒 4、个别可由体内合成 一、vitamine A 1、nature form A1 retinol A2 3-dehydroretinol 2、chemical structure 20-carbon alcohols formed of isoprene units 4、transform NADP NADPH Retinol retinal retinoic acid 5、active form 6、physiological function ① 视觉细胞的感光成分----11-cis-retinal 暗视觉---rod cells， rhodopsin (11-cis-retinal+opsin) visible light—圆椎细胞、视红质、 视蓝质、视青质 visual cycle 二、vitamine D 1、nature forms D2 ergocalciferol D3 cholecalciferol 2、 chemical structure a group of sterol compounds 3、occur Liver (fish liver) 、milk、egg 、 4、transform 7-dehydrocholesterol (in skin) （an inactive precursor of vitamine D) sun light D3 麦角固醇 （plant、yeast ） sunlight D2 5、active form 1，25-（OH）2-D3 6、physiological function regulation of Ca 2+,phosphate, metabolism (small intestine,bone,kidney) 7、 deficiency defe