NHS临床指南 Sepsis and Catheter Associated Urinary Tract infections (CAUTI’s)PPT.ppt

* life-threatening organ dysfunction due to a dysregulated host response to infection”. In simple terms this means that there is an impairment in how an organ normally functions and interference in the body’s normal process of how it reacts to an infection. The new criteria are based on just three symptoms: ?Altered mental status ?Fast respiratory rate ( 22 breaths/minute) ?Low blood pressure (≤ 100 mm Hg systolic) Sepsis is caused by the way the body responds to germs, such as bacteria, getting into your body. The infection may have started anywhere in a persons body, and may be only in one part of the body or it may be widespread. Sepsis can occur following chest or urine infections, problems in the abdomen like burst ulcers, or simple skin injuries like cuts and bites. Sepsis can be caused by a huge variety of different bugs, most cases being caused by common bacteria which we all come into contact with every day; without them making us ill. Sometimes, though, the body responds abnormally to these infections, and this causes sepsis. Sepsis is a life threatening condition that arises when the body’s response to an infection injures its own tissues and organs. Sepsis leads to shock, multiple organ failure and sometimes death especially if not recognized early and treated promptly. In sepsis, the bodys immune system goes into overdrive as it tries to fight an infection. Sepsis can reduce the blood supply to vital organs such as the brain, heart and kidneys. * Without quick treatment, sepsis can lead to multiple organ failure and possibly death. Sepsis ranges from less to more severe. As sepsis worsens, the blood flow to vital organs, such as the brain, heart and kidneys, becomes impaired. Sepsis can also cause blood clots to form in organs and in the arms, legs, fingers and toes leading to varying degrees of organ failure . This can result also cause damage to tissues which can lead to tissue death (gangrene). When this occurs limbs may need to be amputat