术前感染性疾病筛查.ppt

* * * * * * * * 感染过程：感染后在淋巴内大量复制，抗原上升，免疫应答出现抗体 窗口期主要是以能否检测出HIV抗体为定义的，选择抗体、抗体IgG IgM都可能造成不同（两个层次） 检测试剂经历了四代的更替：The first HIV tests has a seroconversion window of 30-40 days. Second and Third generation assays narrowed that window to approximately 23-25 days. 4th Generation HIV Combo tests – tests that combine antibody detection with antigen detection – allow us to narrow the window another 3-5 days (15-17 days after infection). 雅培高灵敏度combo试剂的检测，包括了1 2 O型病毒抗体以及P24抗原 * * * * 2004 HCV audio web conference, Dr.ER Schiff, Miami University, Florida Symptoms +/- Time after Exposure Titer anti-HCV