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An outlook on x-ray CT research and development
Ge Wanga and Hengyong Yub
Biomedical Imaging Division, VT-WFU School of Biomedical Engineering and Science, Virginia Polytechnic
Institute and State University, Blacksburg, Virginia 240601
Bruno De Manc
CT and X-ray Laboratory, GE Global Research, Niskayuna, New York 12309
Received 5 October 2007; revised 20 December 2007; accepted for publication 20 December 2007;
published 25 February 2008
Over the past decade, computed tomography CT theory, techniques and applications have under-
gone a rapid development. Since CT is so practical and useful, undoubtedly CT technology will
continue advancing biomedical and non-biomedical applications. In this outlook article, we share
our opinions on the research and development in this field, emphasizing 12 topics we expect to be
critical in the next decade: analytic reconstruction, iterative reconstruction, local/interior reconstruc-
tion, flat-panel based CT, dual-source CT, multi-source CT, novel scanning modes, energy-sensitive
CT, nano-CT, artifact reduction, modality fusion, and phase-contrast CT. We also sketch several
representative biomedical applications. © 2008 American Association of Physicists in Medicine.
DOI: 10.1118/1.2836950
Key words: analytic reconstruction, iterative reconstruction, local/interior reconstruction, flat-panel
based CT, dual-source CT, multi-source CT, scanning mode, energy-sensitive CT, nano-CT, artifact
reduction, modality fusion, phase-contrast CT
I. INTRODUCTION source CT scanner and other similar systems. Early 1990s,
single-slice helical/spiral CT became the s
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