microRNA miR 144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease英文文献.pdfVIP

2010 116: 4338-4348 Prepublished online Aug 13, 2010; doi:10.1182/blood-2009-04-214817 microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease Carolyn Sangokoya, Marilyn J. Telen and Jen-Tsan Chi Updated information and services can be found at: /cgi/content/full/116/20/4338 Articles on similar topics may be found in the following Blood collections: Red Cells, Iron, and Erythropoiesis (168 articles) Information about reproducing this article in parts or in its entirety may be found online at: /misc/rights.dtl#repub_requests Information about ordering reprints may be found online at: /misc/rights.dtl#reprints Information about subscriptions and ASH membership may be found online at: /subscriptions/index.dtl Blood (print ISSN 0006-4971, online ISSN 1528-0020), is published semimonthly by the American Society of Hematology, 1900 M St, NW, Suite 200, Washington DC 20036. Copyright 2007 by The American Society of Hematology; all rights reserved. RED CELLS, IRON, AND ERYTHROPOIESIS microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease Carolyn Sangokoya,1-3 Marilyn J. Telen,4 and Jen-Tsan Chi1,2 1The Institute for Genome Sciences and Policy, 2 Department of Molecular Genetics and Microbiology, 3University Program in Genetics and Genomics, and 4 Division of Hematology, Department of Medicine, Duke University School of Medicine, Durham, NC Although individuals with homozygous ance for oxidative stress, yet the basis for tion and attenuated antioxidant ca