Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics英文文献.pdfVIP

REVIEW Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics 1* 1* 1 1 1 1 2 2 X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, . J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir,2,4 S. Weiss1,3* results in intermittent fluorescence (blinking) Research on fluorescent semiconductor nanocrystals (also known as quantum dots or visible at the single-molecule level ( 7) and qdots) has evolved over the past two decades from electronic materials science to reduces the overall quantum yield, which is biological applications. We review current approaches to the synthesis, solubilization, the ratio of emitted to absorbed photons. One and functionalization of qdots and their applications to cell and animal biology. Recent way to overcome these problems, and to examples of their experimental use include the observation of diffusion of individual protect surface atoms from oxidation and glycine receptors in living neurons and the identification of lymph nodes in live animals other chemical reactions, is to grow a shell of by near-infrared emission during surgery. The new generations of qdots have far- a few atomic layers of a material with a reaching potential for the study of intracellular processes