precipitating factors and laboratory investigations at the time of presentation in patients with diabetic ketoacidosisword论文.docxVIP
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precipitating factors and laboratory investigations at the time of presentation in patients with diabetic ketoacidosisword论文
AbbreviationsTableAbbreviationsFullEnglishnameDKADiabeticketoacidosisDMDiabetesmellitusPFPrecipitatingfactorPGPlasmaglucoseS.K+SerumpotassiumS.Na+SerumsodiumS.CreSerumcreatinineBUNBloodureanitrogenWBCWhitebloodcellLISTOFCONTENTSPrecipitating FactorsandLaboratoryInvestigations attheTimeofPresentationinPatientswith DiabeticKetoacidosisStudent:Syed Bakht RuidarInstructor: AssociateprofessorABULIKEMU TUERDIAbstractBackground:Diabeticketoacidosis(DKA)isanacutemetaboliccomplicationofdiabetes mellitus.Thepurposeofthisstudyhastomeasuretheprecipitatingfactorsandtherelated laboratoryinvestigationsatthetimeofpresentationwhenthepatientswithDKAcometo theteachinghospitalofxmu.PatientsandMethods:Therewere134diabetesmellitus patients,hospitalizedwithDKAfrom2ndJanuary2011to23rd October2013.Wegetthe patientdatabyseeingthemedicalreportsinEndocrinologyandDiabetesDepartment. Thenwedividedpatientsinto3groupswhichwereonthebasisoftheirbasedonthe sharpness of the diseaseand the precipitatingfactors for diseasesharpnesswere recognized byanalyzingthese3groups.Results:In134DKApatients,61(45.52%)weremildDKA;meanage40.29±17.39,63(47.01%) weremoderateDKA, mean age37.51±16.38 and 10(7.46%) weresevere DKA, meanage31.5±12.76.Discontinuationorinadequateinsulintherapywascommon precipitating factorinthethreegroups(32.78%,38.09%and50%) butthesecondcommon precipitating factorinmildDKAwasinfection(27.87%),inmoderateDKAwasnewonset diabetes(28.57%)andinsevereDKAinfectionandnewonsetdiabeteswereinsameratio (20%each).Thelaboratorytestresultsshowedthattheplasmaglucose,serumpotassium, serumsodium,serumcreatinine,bloodureaandbloodWBCwereincreasedinseverity frommildtomoderateandtosevere.Conclusion:Inthisstudy,discontinuationor inadequateinsulintherapywasmorecommonprecipitatingfactorofDKA,followedby infectionandnewonsetdiabetes.Theabnormalitiesoflaboratorytestsoccurredduetothe hyperglycemiaandmetabolicacidosis.Patientknowledgerelatedtotheimportanceof insulinuse,thedrugshavetobetherefortreatingthetemperatureandaswel
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