生物反应工程chapenzyme讲解课件.pptVIP

Enzyme * * Chapter 2 Enzymes Reduced DsbA from E. coli Lysozyme §2.1 Introduction Definition History Büchner, 1897: A breakthrough in Enzymology. Catalysts at work in a living organism could also function completely independently of any life process. Efforts to isolate and purify individual enzymes were Büchner’s discoveries. Sumner, 1926: First isolation of a pure enzyme. Enzymes are usually proteins of high molecular weight (15,000 MW several million Daltons) that act as catalysts. Characteristics Three-dimensional structure of the folded protein, determined by the sequence of the amino ac