慢性心衰患者的rdw与nt-probnp和cysc的相关性分析及临床意义.docVIP

慢性心衰患者的RDW、CysC与NT-proBNP的相关性分析及临床意义 潘祥坡 （潍坊市人民医院，261041） [摘要] 目的：探讨红细胞分布宽度（RDW））RDW≥14.4%（B组，126人）分成两组，结合随访情况，观察每组患者的NT-proBNP、CysC以及死亡的百分率并作比较。结果：CHF患者的RDW 、NT-proBNP、CysC明显高于健康对照组，并随着NYHA心功能分级的增加而升高，高RDW组的患者的死亡率明显升高，RDW与NT-proBNP，CysC与NT-proBNP，RDW与CysC成正相关。结论：RDW、CysC和NT-proBNP同样可作为心衰预后的预测因子，RDW能够作为心衰患者的发病率和死亡率的一个敏感的独立预测因子可能的机制之一与心衰患者的早期肾功能受损有关。 [关键词] 慢性心衰（CHF））correlation analysis and clinical significance from RDW, CysC and NT - proBNP of the patients with Chronic heart failure Pan Xiang Po （wei fang shi ren min yi yuan,261041） [Abstract] Objective: To explore the relationship between red cell distribution width ( RDW ), cyscatin C ( CysC ) ,N-terminal pro – B- type natriuretic peptides ( NT-proBNP ) and heart function classification and prognosis of the disease in patients with chronic heart failure ( CHF ). Methods: Finished a retrospective analysis of 532 medical records from my hospital patients with CHF from 2008 to 2012, observed the RDW,CysC, NT-proBNP, and compared with 156 healthy controls; according to the different NYHA classification, divided the patients into three groups ,observed the RDW , CysC, NT-proBNP of each group, and compared with them; according to RDW14.4% ( group A, 406 people ) RDW≥ 14.4% (group B, 126 people ) , divided the patients into two groups,observed the differentence of NT-proBNP, CysC and the mortality according to the situation of the follow-up .results: the RDW, NT-proBNP, CysC of the patients with CHF were significantly higher than those in healthy control group, and they increased with NYHA classification grading , the mortality of the patients with high RDW increased significantly, RDW withNT-proBNP, CysC with NT-proBNP, RDW with CysC were positively correlated. Conclusions: As well as NT-proBNP,RDW, CysC can be used as a predictor of prognosis of HF, one of the mechanism that RDW can be as a sensitive and independent predictor of morbidity and mortality in heart failure patients with heart failure patients may be e