柴胡与葛根的不同剂量比例.docVIP

蚌埠医学院 探索性实验论文 题目：柴胡与葛根的不同剂量比例 配伍对小鼠酒精性肝损伤的保护作用 实验小组： 一班二组 专 业： 生物科学 年 级： 2008级 指导教师： 张静 讲师 二零一一年 五 月 二十四 日 目 录 一、中文摘要、关键词 3 二、英文摘要、关键词 3 三、论文正文 4 前言 4 1.实验材料 4 2.材料方法 4 3.结果 5 4.讨论 6 5.致谢 7 6.参考文献 7 柴胡与葛根的不同剂量比例 配伍对小鼠酒精性肝损伤的保护作用 张丹，庞智，汪霁，刘飞，阮海文，刘传杰，吴璇 (蚌埠医学院,安徽,蚌埠) 指导老师:张静 摘要 目的:以柴胡、葛根为研究对象,观察两种单味药以及按不同剂量比例配伍后对酒精所致小鼠肝损伤的保护作用。方法:用0.10 ml/10 g55度北京红星二锅头灌胃造模，以血清谷丙转氨酶(ALT)活性肝中丙二醛（MDA）的Protective Effects of Different Dosage and Prescription of Bupleurum and puerarin on Rat’s Acute Liver Damage Caused by alcoholic Zhangdan,PangZhi,WangJi,LiuFei,RuanHaiWen,LiuChuanJie,WuXuan (Bengbu medical college, anhui, bengbu) Abstract Objective: To observe the protective effects of different dosage and prescriptions of Bupleurum and puerarin on rats acute liver damage caused by alcoholic. Method: alcoholic was irritated to make rats models with the dosage of 0.1 ml/10g. Compared to the index of the content of serum ALT,MDA, Liver samples were observed pathologically with paraffin section and hematoxylin-eosin staining.The protective effect of Bupleurum and puerarin and its prescription on liver damage was observed. Results: Bupleurum and puerarin and its prescriptions can evidently decrease the content of ALT and MDA in blood serum. Conclusion: Bupleurum and puerarin and its prescriptions have a certain protective effect on liver damage caused by alcoholic. and the rate of Bupleurum and puerarin (1∶1)has a more obvious