[所有分类]ERP高级培训班讲座.ppt

ERPs 实验高级培训 It is an exciting time for studying human cognition. ----- Picton, Alain, McIntosh Event-related potentials Event-related brain potentials 凡是外加一种特定的刺激，作用于感觉系统或脑的某一部位，在给予刺激或撤消刺激时，在脑区引起的电位变化。 * 刺激缺失 潜伏期：早、中、晚成份，慢波 命名：正－P，负－N，潜伏期 成份：外源性成份、内源性成份和纯心理波 伪迹的剔除 密切监测非脑电伪迹 实验前告知被试关于伪迹的注意事项以减少伪迹 确定伪迹的剔除标准 EOG的去除(相关法) PCA/ICA SVD Spatial Filter Note: The initial encoding of information (e.g., emotion; EMMN - L Zhao, et al., 2006, 2007) may be relatively attentional resource-free but that top-down, controlled processes become involved as more time passes. fMRI methodology is unable to separate relatively fast versus slow encoding processes due to the slow time course of the hemodynamic response (e.g., Aguirre, et al, 1998; Miezin, et al, 2000) Spatial Singular Value Decomposition (SVD) and Spatial Filtering for Artifact Extraction Visual Evoked Potentials Recorded During Sparse fMRI Sequence (reverse checkboard) Visual Evoked Potentials Recorded at Electrode Oz Visual Evoked Potentials Recorded During Sparse fMRI Sequence 行为数据测量 反应时、正误率 反应时的重要性 （举例） 平均波幅测量 固定法/连续测量 具体法或间断法 （1）测量比较峰潜伏期、 始潜时、波幅 （2）波形的头皮分布 （3）定位分析 Band Analysis Evoked－time-phase locked Induced－time-, non-phase locked ERD/ERS Event-related desynchronization Event-related synchronization Coherence Analysis ….. 偶极子（Dipole） 是一对数值相等、符号相反的电荷，彼此相隔一定距离时形成的体系。 ERPs成份的源 即脑内的偶极子。神经传导递质作用于突触后神经元受体的过程中产生的突触后电位导致了ERPs的产生(Luck,1998)。头皮电位的分布取决于电流偶极子的位置与方向。 源定位 可根据偶极子的数目、时间特征、位置和偶极子量等因素推导。 偶极子模型－single/multiple dipole models The error must be detected, the guilt or frustration must be acknowledged, and compensatory behavior must be initiated. Ne---notice errors Pe---cope with errors Language Processing Linguistics Word Sentence Context Learning Semantic Syntax Visual and auditory modality …… Mirror effect of Chinese word perce