参松养心胶囊抗心律失常的有效性和安全性.DOCVIP

参松养心胶囊抗心律失常的有效性和安 全性 徐克明李明王素萍 重庆市开州区人民医院药剂科 R的:观察参松养心胶囊抗心律失常的临床疗效和不良反应，评价其抗心律失常 的有效性和安全性。方法:将2015. 07—2017. 05我院收治的360例心律失常患荠 随机分为对照组和观察组，每组180例，M组患者均给予常规治疗，观察组另 给予参松养心胶囊口服，4粒/次，每日3次;对照组另给予其普罗帕酮口服， 150mg/次，每日3次，疗程均为4周。详细记录两组患者在用药前、用药吋、随 访时的临床症状，以及心电图和动态心电图、血压、心率、H肠道不良反应等情 况，比较两组心律失常患者在临床症状改善、心电图疗效及不良反应的发生情 况。结果：临床症状改善比较，观察组总有效率为88. 9%,对照组为65. 6%,观察 组优于对照组，P〈0.05,差异有统计学意义;心电图疗效比较，观察组为75.0%, 对照组为52. 8%,观察组优于对照组，P〈0.05,差异有统计学意义。参松养心胶 囊对心律失常疗效满意丑未见致心律失常、胃肠道紊乱等不良反应。结论:参松 养心胶囊用来治疗心律失常有效且安全，值得临床推广。 关键词： 参松奍心胶囊;普罗帕酮;心律失常;奋效性;安全性; 电 话：023 电 话：023 Efficacy and Safety of Shen Song Yang Xin Capsule for Cardiac Arrhythmia XU Ke-ming LI Ming WANG Su-ping Dept. ofPharmacy, The peonle，sHosnital of Kaizhou District, Chongqing; Abstract： Objective: To observe the clinical efficacy and adverse effects of Shen Song Yang Xin capsule on anti-arrhythmic, to evaluate the efficacy and safety of Shen Song Yang Xin capsule for cardiac arrhythmia. Methods: 360 patients with arrhythmia in our hospital from 2015. 07 to 2017. 05 were randomly divided into control group and observation group. 180 patients in each group were given routine treatment. The observation group was given oral administration of Shen Shen Yang Xin capsule, 1. 6 g three times a day, the control group was given propafenone oral, 150 mg three times a day, treatment are 4 weeks. To investigate the cl inical symptoms, electrocardiogram and ambulatory electrocardiogram, blood pressure, heart rate and gastrointestinal adverse reactions in the two groups before and after treatment, arrhythmia in clinical symptoms, electrocardiogram efficacy and the incidence of adverse reactions were compared of two groups of patients. Results: Comparison of clinical symptoms, the total effective rate was 88. 9% in the observation group and 65- 6% in the control group. The treatment group was better than the control group, P0. 05，the difference was statistically significant; electrocardiogram comparison, 75. 0% in the observati