共聚焦激光扫描硬质胆囊镜的研发.PDFVIP

著 K 论 R O 究 W 研 H 共聚焦激光扫描硬质胆囊镜的研发 C R A E The Research and Design of the Hard Cholecystoscope of Confocal S E R Laser Scanning 1,2 1,2 1,2 [摘 要] 本文具体介绍一种共聚焦激光扫描硬质胆囊镜的研发技术。该内镜的研发成功并投入使 乔铁 ，黄万潮 ，谢景夏 ，何 群芝1,2 用，将使得对胆囊病的研究进入微观层面，在活体细胞的状态下对病变组织进行共聚焦激光扫 1.卫生部肝胆肠外科研究中心 胆囊 描，对获得的图谱进行病理对照分析，对胆囊的病变作出准确的诊断。 疾病研究所，广东 番禺 511470； [关键词] 胆囊镜；共聚焦技术；显微CT；微创外科；胆囊检查 2.广州市番禺区第二人民医院，广东 番禺 511470 Abstract: This paper introduces the development of the hard cholecystoscope of confocal laser scanning, which combined the confocal laser scanning system and the hard cholecystoscope. The hard cholecystoscope of confocal laser scanning can do the laser scanning when the cells are alive, and can provide the microcosmic images with the gallbladders pathological changes. By comparing these images, the doctors QIAO Tie1, 2, HUANG Wan-chao1,2, can make the precise diagnosis. XIE Jing-xia1,2, HE Qun-zhi1,2 Key words: cholecystoscope; confocal technology; micro-CT; minimal-invasive surgery; gallbladder 1. Institute of Gallbladder Disease of examination NHEC, Institute of Gallbladder Disease of + Panyu, Panyu Guangdong 511470, China; [中图分类号] TH776 .1 [文献标志码] A 2. The Second Peoples Hospital of Panyu, doi：10.3969/j.issn.1674-1633.2011.01.010 Panyu Guangdong, 511470, China [文章编号] 1674-1633(2011)01-0038-03 本文导读 课题背景 ：共聚焦显微硬质胆囊镜，是结合先进的共聚焦激光扫描技术的创新产品，为胆囊病的诊断提供细胞级的图像依据。该内镜 系统已获得国家实用新型专利授权。 重要概念：共聚焦技术是指光路（激发和发射）在两个位置上聚焦，有效防止杂质信号产生的背景噪音干扰，从而降低背景信号的强度， 突出目标组织的强度，获得高质量的图像。共聚焦最核心的技术是通过空间过滤技术去