Levodopa in the treatment of Parkinsons disease current…左旋多巴治疗帕金森病目前.pdfVIP

Movement Disorders Vol. 19, No. 9, 2004, pp. 997–1005 © 2004 Movement Disorder Society Research Review Levodopa in the Treatment of Parkinson’s Disease: Current Controversies C. Warren Olanow,1* Yves Agid,2 Yoshi Mizuno,3 Alberto Albanese,4 U. Bonucelli,5 Philip Damier,6 Justo De Yebenes,7 Oscar Gershanik,8 Mark Guttman,9 F. Grandas,10 Mark Hallett,11 Ole Hornykiewicz,12 Peter Jenner,13 R. Katzenschlager,14 William J. Langston,15 Peter LeWitt,16 Eldad Melamed,17 M.A. Mena,18 P.P. Michel,19 Catherine Mytilineou,20 Jose A. Obeso,21 Werner Poewe,22 Niall Quinn,23 R. Raisman-Vozari,24 Ali H. Rajput,25 Olivier Rascol,26 Christina Sampaio,27 and Fabrizio Stocchi28 1Department of Neurology, Mount Sinai School of Medicine, New York, New York, USA; 2Hopital de la Salpetriere, Paris, France; 3Department of Neurology, School of Medicine, Jutendo University School of Medicine, Bunkyo-Ku, Tokyo, Japan; 4Istituto Nazionale Neurologico, Milano, Italy; 5Department of Neuroscience, University of Pisa, Capezzano-Pianore, Italy; 6Hopital Laennec, Clinique Neurologique, Nantes, France; 7Fundacio´n Jime´nez Dı´az, Universidad Auto´noma de Madrid, Madrid, Spain; 8Hopital Frances, Centro Neurold”gico, La Rioja, Buenos Aires, Argentina; 9 University of Toronto, Markham, Ontario, Canada; 10Hopital General G Maranon, Libertad, Velilla De San Antonio, Madrid, Spain; 11Human Motor Control Section, National Institute of Neurological Disease Center, National Institutes of Health, Bethesda, Maryland, USA; 12Brain Research Institute, Vienna University Medical School, Vienna, Austria; 13King’s College London, Hodgkin Building, Guy’s Campus, London, United Kingdom; 14National Hospital for Neurology and Neurosurgery, London,