胱抑素C对判断儿童过敏性紫癜早期肾损害的临床-第三军医大学学报.DOC

胱抑素C对判断儿童过敏性紫癜早期肾损害的临床-第三军医大学学报.DOC

胱抑素C对判断儿童过敏性紫癜早期肾损害的临床-第三军医大学学报

《第三军医大学学报》编辑部: 你好! 第一作者:陶红 TAO Hong 性别:女 学历:硕士 学位:硕士 研究方向:肾脏免疫 工作单位:攀枝花市中心医院儿科(Panzhihua Central Hospital of Pediatrics) 单位所在省份:四川省 通讯地址:攀枝花市中心医院儿科 邮政编码:617000 联系电话E-mail:lilutaohong@163.com 本人曾于2007年7月至2010年7月在重庆医科大学附属儿童医院攻读硕士学位,读书期间共发表3篇文章,分别为 [1]陶红,李秋.自身免疫性疾病治疗的新靶点[J].实用儿科临床杂志,2009,24(9):705-708. [2]陶红,李秋,王莉,等.过敏性紫癜发病中树突状细胞与T辅助细胞分化失衡的关系[J].第三军医大学学报,2010,32(7):677-679. [3]陶红,李秋,王莉佳,等. 儿童过敏性紫癜发病中NF-κB对树突状细胞的调控与T辅助细胞分化失衡的关系[J].第三军医大学学报,2010,32(23):2519-2523. 胱抑素C对判断儿童过敏性紫癜早期肾损害的临床价值 陶红1 , 王岭1 , 肖红1 ,吴祥1 , 郭江1 ,黎晓兰1 ,李秋2 1.攀枝花市中心医院(攀枝花 617000);2.重庆医科大学附属儿童医院(重庆 400014) [摘要] 目的 通过联合检测血清胱抑素C(Cys C)与尿,探讨其在儿童过敏性紫癜(HSP)早期肾脏损害诊断中的临床价值。Clinical value of cystatin C in predicting early renal damage in children with Henoch-Schonlein purpura Tao Hong1,Wang ling1,Xiao hong1,Wu xiang1,Guo jiang1 ,Li XiaoLan1,Li Qiu2 1.PanzhihuaCentral Hospital (Panzhihua 617000, China )2.The Children’s Hospital of Chongqing Medical University ,(Chongqing 400014,China) [Abstract] Objective Through the combined detection of serum cystatin C (Cys C) and urinary immunoglobulin and transferrin, study the clinical value of early diagnosis of renal damage in children with Henoch-Schonlein purpura (HSP).Methods According to the endogenous creatinine clearance rate of 100 cases of children with Henoch-Schonlein purpura were divided into two groups, group B included 58 patients without renal damage, 42 cases in group C with renal damage.The other same age children in outpatient health examination in 50 cases of normal control group, group A, using nephelometric immunoassay for detection of urinary immunoglobulin and transferrin and solution for [基金项目]四川省卫生厅课题110643;攀枝花市软科学研究项目2012 CY-S-22(3) determination of CysC by turbidimetry. Results Compared with the control group, in children with Henoch-Schonlein purpura cystatin C and urinary immunoglobulin and transferrin increased significantly (P 0.05), renal injury group increased more obviously. Conclusion CysC co

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