如何制定mCRC姑息治疗策略章必成教材教学课件.pptxVIP

如何制定mCRC的姑息治疗策略.整体治疗策略的应用显著延长了mCRC患者的OS中位OS3020100BSC5-FU伊立替康1卡培他滨2奥沙利铂3贝伐珠单抗4时间 (月)西妥昔单抗5,6帕尼单抗7阿柏西普8瑞戈非尼9*可溶性VEGFR：阿柏西普小分子TKI：瑞格非尼 1980s 1990 2000s 20101. Cunningham, et al. Lancet 1998; 2. Van Cutsem, et al. BJC 2004; 3. Rothenberg, et al. JCO 20034. Hurwitz, et al. NEJM 2004; 5. Cunningham, et al. NEJM 2004; 6. Van Cutsem, et al. NEJM 20097. Van Cutsem, et al. JCO 2007; 8. Van Cutsem, et al, JCO 2012; 9. Grothey, Van Cutsem, et al. Lancet 2012整体治疗策略=充分运用+合理布局有效药物一线治疗奥沙利铂/伊立