心血管疾病合并糖尿病的药物选择原则教材教学课件.pptVIP

列奈类同样具有严重的低血糖反应，Culy CR等研究发现，瑞格列奈低血糖发生率与磺脲类相当（16％，VS.18％），只不过磺脲类的严重低血糖反应略高于瑞格列奈，瑞格列奈少吃一餐的低血糖风险低于磺脲类。由此说明瑞格列奈低血糖的不良反应同样是严重的。 In 1-year trials, the most common adverse events reported in repaglinide recipients (n = 1,228) were hypoglycaemia (16%), upper respiratory tract infection (10%), rhinitis鼻炎 (7%), bronchitis支气管炎 (6%) and headache (9%). The overall incidence of hypoglycaemia was similar to that recorded in patients receiving glibenclamide, glipizide or gliclazide (n = 597) [18%]; however, the incidence of serious hypoglycaemia appears to be slightly higher in sulphonylurea recipients. U