对抗致病菌的新的抗毒性方法(英文课件)A new antivirulence approach against pathogenic bacteria.pptVIP

 A new antivirulence approach against pathogenic bacteria ;Corporate overview;MUTABILIS’ research objectives;Background: Medical need for new anti-infective therapies;Pathogenic bacteria use a range of virulence factors to establish infection;MUTABILIS’ approach to virulence; Drug approach: Selective inhibition of pathogenic bacteria by targeting virulence factors necessary for bacterial spreading in blood Virulence inhibitors do not perturb development of commensal bacteria Diminished risk of developing resistant mutants because of lower selective pressure This lead to the discovery of ne