抗生素课件课件(英文精品) Metabolic engineering of bacteria.pptVIP

Metabolic engineering of bacteria;Many biological small molecules are useful;Increasing production of antibiotics (and other small molecules)--traditional methods;An alternative to simple random mutagenesis: genome shuffling;The shuffling advantage: simultaneous recombination of entire genomes (breeding) with multiple parents;The set-up;Supplements required: pro, arg, ura (not cys) pro, cys, ura (not arg) arg, cys, ura (not pro) pro, arg, cys (not ura);;Increasing production of a biological compound: rational design;Engineering E. coli to produce indigo Mutate tryptophan synthase complex t