(精编)【医学教学课件大全】 针刺镇痛研究教学课件.pptVIP

针刺镇痛研究40年回顾;历史回顾;从 “是什么” What？ 针刺真的镇痛吗？ 到 “为什么” Why？ 针刺为什么会镇痛？;Acupucture-induced analgesia Human Observation:;Site specificity;痛阈变化百分数;;测痛是否能预测针麻效果？;合谷穴内注射局麻药procaine阻断针刺镇痛;Procaine infiltration in the acupoint abolishes the effect of AA;Decay of the Effect of Acupuncture Analgesia After the termination of acupuncture stimulation Half life (T1/2) = 16 min;Rabbit experiment: cross infusion of CSF;从 “是什么” What？ 针刺真的镇痛吗？是的！ 到 “为什么” Why？ 针刺为什么会镇痛？;机制研究从何入手？;针刺镇痛的神经化学机制;Tail flick latency, % change; The role of CNS NA in EA analgesia;中枢神经递质在脑的不同部位 发挥不同作用;; 2Hz EA increases Enk release 100Hz EA increases Dyn release;0;15;电针不同频率 发挥不同作用;放电频率;2 Hz;Synergistic Interaction between neuropeptides; The optimal cycle of DD wave;Trends in Neuroscience, 2003; 26: 17-22 ;电针方法 是否有改进余地？;穴位接受什么刺激？;电刺激穴位：两种方式;电针 via needles;;Cross tolerance between EA and TENS;电针和TENS的比较;HANS for the treatment of autism自闭症、孤独症;电针镇痛的神经通路; Nerve pathways for low and high frequency EA analgesia ;Nerve pathways for low and high frequency EA analgesia ;Brain imaging and functional correlates;29;R. Primary Motor Area (R-MI);31;从原理研究 返回临床实际;Han’s Acupoint Nerve Stimulator (HANS) 韩 氏 穴 位 神 经 刺 激 仪;Electrical stimulation parameters;急性痛 （创伤，手术，术后，生育…);0;针刺镇痛的积累效应 疗效增强，作用时间延长。;The Longlasting Effect of Electroacupuncture on Cold-induced Neuropathic Pain;Cumulative effect of EA on spinal spasticity;针刺积累效应的可能机制 促进有关基因的表达;Electroacupuncture accelerates the gene expression (prepro-enkephalin) in rat brain;Naive;2Hz EA increased the level of PPE mRNA in nucleus accumbens of CPP rats;PPD (250 bp);Dr. Paul White, University of Texas, South Western Medical Center and his group Wang, B.G. et al. (1997) Effect of the intensity of transcutaneous acupoint electrical stimulation on the postoperative analgesic requirement. Anesth. Analg. 85, 406-13 Hamza, M.A. et al. (1999) Effect of the frequency of transcutaneous electrical nerve stimulation on the postoperati